Camlopril 10 mg+20 mg (Capsule)

Unit Price: ৳ 10.07 (5 x 6: ৳ 302.10)
Strip Price: ৳ 60.42

Medicine Details

Indications

  • Treatment of hypertension
  • Not indicated for initial therapy of hypertension

Pharmacology

  • Inhibition of angiotensin-converting enzyme (ACE)
  • Inhibition of calcium ion influx into vascular smooth muscle and cardiac muscle
  • Peripheral arterial vasodilation
  • Peak plasma concentrations reached at different times for Benazepril and Amlodipine
  • Antihypertensive effect within 1 hour
  • Peak reductions achieved 2-8 hours after dosing
  • Once-daily doses efficacy

Dosage & Administration

  • Effective doses for Amlodipine and Benazepril
  • Initiation therapy criteria
  • Dose titration guidance
  • Replacement therapy option for patients receiving Amlodipine and Benazepril from separate tablets
  • Recommended initial dose for specific patient groups

Interaction

  • Interaction with diuretics
  • Potassium supplements and potassium-sparing diuretics interaction
  • Clinical trials with Amlodipine

Contraindications

  • Contraindicated for patients hypersensitive to Benazepril or any other ACE inhibitor, or to Amlodipine

Side Effects

  • Safety evaluation for at least 6 months
  • Discontinuation reasons for therapy
  • Common side effects
  • Incidence of edema
  • Rare side effects

Pregnancy & Lactation

  • Pregnancy categories
  • Discontinuation recommendation during pregnancy
  • Excretion of Benazepril and Amlodipine in breast milk
  • Recommendation for breastfeeding

Precautions & Warnings

  • Caution in patients with severe renal disease
  • Possible occurrence of hyperkalemia
  • Use in patients with hepatic failure
  • ACE inhibitor-induced cough
  • Effects on hypotension during surgery/anesthesia
  • Carcinogenicity, mutagenicity, and impairment of fertility

Use in Special Populations

  • Clinical experience differences between the elderly and younger patients
  • Safety and effectiveness in pediatric patients not established

Overdose Effects

  • No reported human overdoses with any combination of Amlodipine and Benazepril
  • Reports of human overdoses with Benazepril and other ACE inhibitors

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Temperature and environmental storage requirements
  • Protection from light and moisture
  • Keep out of reach of children

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