Olmefast-AM 5 mg+40 mg (Tablet)
Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | Goodman pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension alone or with other antihypertensive agents
- Lowering blood pressure
- Initial therapy for patients likely to need multiple antihypertensive agents
- Individualized blood pressure goals based on patient risk
Pharmacology
- Amlodipine as a dihydropyridine calcium channel blocker
- Greater effect on vascular smooth muscle cells than on cardiac muscle cells
- Peripheral arterial vasodilator
- Olmesartan Medoxomil blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II
Dosage & Administration
- Substitution of individually titrated components
- Initial therapy with 5/20 mg once daily
- Titration up to a maximum of 10/40 mg once daily
- Lower starting dose of Amlodipine for elderly patients
- Not recommended for patients over 75 years old
Interaction
- Potential attenuation of antihypertensive effect by NSAIDs
- Need for close monitoring of blood pressure, renal function, and electrolytes
Contraindications
- Contraindicated with Aliskiren in patients with diabetes
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Risk of sprue-like enteropathy
Pregnancy & Lactation
- Pregnancy Category D
- Avoid use in 2nd and 3rd trimester
- Potential excretion in human milk
- Consideration for discontinuation of nursing
Precautions & Warnings
- Caution in volume- or salt-depleted patients
- Caution in severe aortic stenosis patients
- Caution in patients with severe obstructive coronary artery disease
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety or effectiveness in subjects 65 years of age or older
- No studies in patients with renal impairment
- Initial therapy not recommended in hepatically impaired patients
Overdose Effects
- No information available on human overdosage
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children