Valdipin 5 mg+80 mg (Tablet)

Indications

• Treatment of hypertension

Pharmacology

• Dihydropyridine calcium channel blocker
• Blocks vasoconstrictor and aldosterone-secreting effects

Dosage & Administration

• Once daily doses of 2.5 mg - 10 mg for Amlodipine
• Effective doses of 80 mg-320 mg for Valsartan
• Maximum dosage of 10/320 mg once daily
• Can be administered with or without food
• Can be administered with other antihypertensive agents
• Initiate Amlodipine at 2.5 mg in elderly patients
• No initial dosage adjustment for mild or moderate renal impairment
• Titrate slowly in severe renal impairment
• No initial dosage adjustment for mild or moderate liver insufficiency
• Titrate slowly in hepatic impairment

Interaction

• No specific drug interaction studies for the combination product

Contraindications

• Hypersensitivity to any components of the product

Side Effects

• Mild and transient side effects
• Common side effects include peripheral edema, nasal congestion, sore throat, discomfort when swallowing, upper respiratory tract infection, dizziness

Pregnancy & Lactation

• Pregnancy Category D
• Unknown excretion in human milk
• Consider discontinuing nursing or the drug

Precautions & Warnings

• Avoid fetal or neonatal exposure
• Assess for hypotension
• Warn patients with severe obstructive coronary artery disease
• Titrate slowly in patients with impaired hepatic or severely impaired renal function

Use in Special Populations

• Safety and effectiveness not established in pediatric patients

Therapeutic Class

• Combined antihypertensive preparations

Storage Conditions

• Keep below 30°C
• Away from light & moisture
• Keep out of the reach of children

Related Brands

• Valdipin 5 mg+160 mg (Tablet) - renata-limited
• Co-Disys 10 mg+160 mg (Tablet) - healthcare-pharmaceuticals-ltd