Valdipin 5 mg+160 mg (Tablet)

Indications

• Treatment of hypertension

Pharmacology

• Amlodipine is a dihydropyridine calcium channel blocker
• Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of Angiotensin II

Dosage & Administration

• Amlodipine once daily doses of 2.5 mg - 10 mg
• Valsartan doses of 80 mg-320 mg
• Elderly patients: Therapy should usually be initiated at 2.5 mg
• Renal Impairment: No initial dosage adjustment is required for patients with mild or moderate renal impairment
• Hepatic Impairment: No initial dosage adjustment is required for patients with mild or moderate liver insufficiency

Interaction

• No drug interaction studies have been conducted with Amlodipine and Valsartan combination

Contraindications

• Hypersensitive to any components of this product

Side Effects

• Peripheral edema
• Nasal congestion
• Sore throat
• Upper respiratory tract infection
• Dizziness

Pregnancy & Lactation

• Pregnancy Category D
• Not known whether Amlodipine or Valsartan is excreted in human milk

Precautions & Warnings

• Avoid fetal or neonatal exposure
• Assess for hypotension
• Warn patients with severe obstructive coronary artery disease about the risk of myocardial infarction or increased angina
• Titrate slowly in patients with impaired hepatic or severely impaired renal function

Use in Special Populations

• Safety and effectiveness in pediatric patients have not been established

Therapeutic Class

• Combined antihypertensive preparations

Storage Conditions

• Keep below 30°C temperature
• Away from light & moisture
• Keep out of the reach of children

Related Brands

• Co-Disys 10 mg+160 mg (Tablet) - healthcare-pharmaceuticals-ltd