Locol Plus 5 mg+10 mg (Tablet)
Unit Price: ৳ 11.04 (3 x 10: ৳ 331.20)
Strip Price: ৳ 110.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atorvastatin |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Hypertension
- Chronic stable angina
- Hypercholesterolemia
- Coronary artery disease
- Hyperlipidemia
Pharmacology
- Calcium channel blocker
- HMG-CoA reductase inhibitor
- Peripheral arterial vasodilator
- Lipid-lowering agent
Dosage & Administration
- Initial oral dose of 5mg Amlodipine
- Maximum dose of 10mg Amlodipine
- Starting dose of 10mg Atorvastatin
- Dosage range of 10-80mg Atorvastatin
- Administration with or without food
Interactions
- Cyclosporine
- Fibric acid derivatives
- Niacin
- Erythromycin
- Azole antifungals
- Magnesium and aluminum hydroxide
- Colestipol
- Digoxin
- Warfarin
- Cyclosporine
Contraindications
- Hypersensitivity to Amlodipine
- Hypersensitivity to Atorvastatin
- Active liver disease
Side Effects
- Amlodipine-induced vasodilatation
- Acute hypotension
- Rhabdomyolysis
- Elevation in serum creatine phosphokinase levels
- Myopathy
- Constipation
- Headache
- Nausea
- Insomnia
Pregnancy & Lactation
- Safety not established in pregnancy
- Not recommended during breastfeeding
Precautions & Warnings
- Increased angina and/or myocardial infarction
- Liver dysfunction
- Caution in patients with heart failure
- Rhabdomyolysis
- Elevation in serum creatine phosphokinase levels
Use in Special Populations
- Safety and efficacy not established in children
- Similar efficacy and safety in older patients
Therapeutic Class
- Anti-anginal drugs
- Lipid-lowering drugs
Storage Conditions
- Cool and dry storage
- Protection from light and moisture
- Keep out of reach of children