Clogfree Plus 75 mg+75 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clopidogrel aspirin |
| Company | Asiatic laboratories ltd |
Indications
- Reduction of myocardial infarction (MI) rate
- Reduction of stroke rate
- Treatment of acute coronary syndrome (ACS)
- Treatment of unstable angina (UA)
- Treatment of non-ST-elevation myocardial infarction (NSTEMI)
- Treatment of ST-elevation myocardial infarction (STEMI)
- Reduction of MI and stroke in patients with peripheral arterial disease
- Reduction of recent MI and stroke
Pharmacology
- Inhibition of platelet activation
- Inhibition of platelet aggregation
- Binding of active metabolite to P2Y12 class of ADP receptors
- Dose-dependent inhibition of platelet aggregation
- Irreversible inhibition of platelet cyclooxygenase by aspirin
Dosage & Administration
- Recommended dose of 75 mg once daily
- Option for 300 mg loading dose for acute coronary syndrome
- Concurrent use with aspirin
- No dosage adjustment for elderly patients
- No dosage adjustment for patients with renal impairment
Interaction
- Potentiation of aspirin effect on collagen-induced platelet aggregation
- No need for modification of heparin dose
- Increased risk of occult gastrointestinal blood loss with NSAIDs
- Undetermined safety of co-administration with warfarin
Contraindications
- Hypersensitivity to the drug substance
- Hypersensitivity to any component of the product
- Active pathological bleeding
Pregnancy & Lactation
- Use during first and second trimesters if clearly needed
- Contraindicated during the third trimester
- Discontinuation during breastfeeding
Precautions & Warnings
- Prolongation of bleeding time
- Rare risk of thrombotic thrombocytopenic purpura (TTP)
- Potential development of Reye's syndrome
- Risk of hypersensitivity reactions
Use in Special Populations
- Not recommended for children under 12 years
Overdose Effects
- Bleeding complications with clopidogrel overdose
- Dizziness, headache, tinnitus, confusion in aspirin overdose
- Breathing and acid-base disturbances in severe aspirin overdose
Therapeutic Class
- Anti-platelet drugs
Storage Conditions
- Storage below 30°C
- Protection from light and moisture
- Keep out of reach of children
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