Clogfree Plus 75 mg+75 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Clopidogrel aspirin
Company Asiatic laboratories ltd

Indications

  • Reduction of myocardial infarction (MI) rate
  • Reduction of stroke rate
  • Treatment of acute coronary syndrome (ACS)
  • Treatment of unstable angina (UA)
  • Treatment of non-ST-elevation myocardial infarction (NSTEMI)
  • Treatment of ST-elevation myocardial infarction (STEMI)
  • Reduction of MI and stroke in patients with peripheral arterial disease
  • Reduction of recent MI and stroke

Pharmacology

  • Inhibition of platelet activation
  • Inhibition of platelet aggregation
  • Binding of active metabolite to P2Y12 class of ADP receptors
  • Dose-dependent inhibition of platelet aggregation
  • Irreversible inhibition of platelet cyclooxygenase by aspirin

Dosage & Administration

  • Recommended dose of 75 mg once daily
  • Option for 300 mg loading dose for acute coronary syndrome
  • Concurrent use with aspirin
  • No dosage adjustment for elderly patients
  • No dosage adjustment for patients with renal impairment

Interaction

  • Potentiation of aspirin effect on collagen-induced platelet aggregation
  • No need for modification of heparin dose
  • Increased risk of occult gastrointestinal blood loss with NSAIDs
  • Undetermined safety of co-administration with warfarin

Contraindications

  • Hypersensitivity to the drug substance
  • Hypersensitivity to any component of the product
  • Active pathological bleeding

Pregnancy & Lactation

  • Use during first and second trimesters if clearly needed
  • Contraindicated during the third trimester
  • Discontinuation during breastfeeding

Precautions & Warnings

  • Prolongation of bleeding time
  • Rare risk of thrombotic thrombocytopenic purpura (TTP)
  • Potential development of Reye's syndrome
  • Risk of hypersensitivity reactions

Use in Special Populations

  • Not recommended for children under 12 years

Overdose Effects

  • Bleeding complications with clopidogrel overdose
  • Dizziness, headache, tinnitus, confusion in aspirin overdose
  • Breathing and acid-base disturbances in severe aspirin overdose

Therapeutic Class

  • Anti-platelet drugs

Storage Conditions

  • Storage below 30°C
  • Protection from light and moisture
  • Keep out of reach of children

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