Esoral 20 mg (Oral Powder)

20 mg sachet: ৳ 7.00 (30's pack: ৳ 210.00)

Medicine Details

Category Details
Generic Esomeprazole
Company Eskayef pharmaceuticals ltd
Also available as
Esoral 20 mg tablet Esoral 40 mg tablet Esoral 20 mg capsule Esoral 40 mg capsule Esoral 40 mg injection

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Treatment of duodenal and gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Specific inhibition of H+/K+-ATPase
  • Absorption through enteric-coated pellet formulation
  • Metabolism in the liver by CYP enzymes
  • High plasma protein binding
  • Extensive metabolism
  • Excretion in urine and faeces
  • Combination therapy with antimicrobials

Dosage

  • Oral tablets or capsules
  • Oral suspension administration
  • IV injection or infusion administration
  • Specific dosages for different indications
  • Different dosages for adult and pediatric patients

Administration

  • Tablet or capsule should be swallowed whole
  • Oral suspension to be prepared and administered
  • IV injection to be prepared and administered
  • Specific instructions for nasogastric or gastric tube administration

Interaction

  • Metabolism by CYP2C19 and CYP3A4
  • No inhibition of various CYP enzymes
  • Potential interference with CYP2C19
  • Limited interaction with specific drugs
  • Interaction with oral contraceptives, diazepam, phenytoin, and quinidine

Contraindications

  • Contraindicated in patients with known hypersensitivity

Side Effects

  • Frequently occurring adverse events
  • Commonly reported adverse events

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • No information on excretion in milk
  • Recommendation to discontinue breastfeeding

Precautions & Warnings

  • Symptomatic response does not preclude presence of gastric malignancy
  • Specific instructions for patient information and usage
  • Use of antacids during treatment

Use in Special Populations

  • No established safety and effectiveness in pediatric patients
  • No overall differences in safety and efficacy in geriatric patients
  • No dosage adjustment for mild to moderate hepatic insufficiency
  • No alteration of pharmacokinetics in renal impairment

Overdose Effects

  • Lethal dose in animal studies
  • Signs of acute toxicity
  • No specific antidote
  • Treatment guidance for overdose

Storage Conditions

  • Temperature and environmental storage requirements

Chemical Structure

  • Molecular formula
  • Chemical structure representation

Common Questions about Esoral 20 mg Powder

  • Information about the product's uses
  • Common side effects
  • Use during pregnancy and breastfeeding
  • Onset of action
  • Quick tips for usage

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