Amlozep 5 mg+10 mg (Capsule)
Unit Price: ৳ 6.04 (3 x 10: ৳ 181.20)
Strip Price: ৳ 60.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate benazepril hydrochloride |
| Company | Beacon pharmaceuticals plc |
Indications
- Treatment of hypertension
Pharmacology
- Combination of Amlodipine and Benazepril
- Inhibition of angiotensin-converting enzyme (ACE)
- Inhibition of calcium ion influx into vascular smooth muscle and cardiac muscle
- Peripheral arterial vasodilation
- Absorption rate and extent of Benazepril and Amlodipine
- Antihypertensive effect timeline
- Dosage and administration for hypertension treatment
- Dose titration guided by clinical effect
- Replacement therapy for Amlodipine and Benazepril
- Interaction with diuretics, potassium supplements, and other drugs
- Contraindications for hypersensitive patients
- Side effects evaluation over 6-12 months of therapy
- Pregnancy categories C and D
- Minimal excretion of Benazepril and benazeprilat in breast milk
- Amlodipine excretion in human milk unknown
- Precautions for impaired renal function, hyperkalemia, hepatic failure, cough, surgery/anesthesia
- No evidence of carcinogenicity, mutagenicity, or impairment of fertility
- Geriatric use and pediatric use safety
- Overdose effects
- Therapeutic class of combined antihypertensive preparations
- Storage conditions
Dosage & Administration
- Effective doses of Amlodipine and Benazepril
- Initial therapy considerations
- Dose titration timeline
- Combination therapy benefits
- Replacement therapy for convenience
- Recommended initial dose for specific patient groups
Interaction
- Interaction with diuretics
- Interaction with potassium supplements and potassium-sparing diuretics
- Safety of concomitant use with other medications
Contraindications
- Hypersensitivity to Benazepril or ACE inhibitors
- Hypersensitivity to Amlodipine
Side Effects
- Evaluation of side effects over 6-12 months of therapy
- Discontinuation reasons
- Common side effects
- Gender-specific side effects
- Rare side effects
Pregnancy & Lactation
- Pregnancy categories
- Discontinuation recommendation during pregnancy detection
- Excretion of Benazepril and benazeprilat in breast milk
- Amlodipine excretion in human milk
Precautions & Warnings
- Caution in severe renal disease
- Risk of hyperkalemia
- Caution in patients with hepatic failure
- Consideration of ACE inhibitor-induced cough
- Caution during surgery and anesthesia
- Carcinogenicity, mutagenicity, and fertility assessment
Use in Special Populations
- Geriatric use safety
- Pediatric use safety
Overdose Effects
- Reported human overdoses
- Absence of death reports
Therapeutic Class
- Category of combined antihypertensive preparations
Storage Conditions
- Temperature and environmental requirements
- Safety precaution for children