Telmivas AM 5 mg+40 mg (Tablet)
Unit Price: ৳ 12.50 (3 x 10: ৳ 375.00)
Strip Price: ৳ 125.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate telmisartan |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension
- Combination therapy
- Initial therapy for blood pressure control
Pharmacology
- Fixed dose combination of Telmisartan and Amiodipine
- Angiotensin receptor blocker (ARB)
- Calcium-channel blocker (CCB)
- Effects on renin-angiotensin system
- Vasoconstriction inhibition
- Vascular smooth muscle dilation
- Blood pressure reduction
Dosage & Administration
- Initial dose of 40/5 mg once daily
- Alternate dosages for larger blood pressure reductions
- Add-on therapy for inadequate control
- Replacement therapy for component doses
- Individualized dosage
- Maximum recommended dose of 80/10 mg once daily
Interaction
- No significant interaction with specific drugs
- Metabolism by cytochrome P450 system
- Inhibition of CYP2C19
- Safe co-administration with various drugs
Contraindications
- Hypersensitivity to product components
- Pregnancy and lactation
- Biliary obstructive disorders
- Severe hepatic impairment
- Hypotension
- Cardiogenic shock
- Left ventricle outflow tract obstruction
Side Effects
- Dizziness
- Peripheral edema
- Migraine
- Headache
- Hypotension
- Cough
- Abdominal pain
- Diarrhea
- Nausea
- Pruritus
- Myalgia
- Erectile dysfunction
- Chest pain
- Fatigue
Pregnancy & Lactation
- Pregnancy Categories C and D
- Excretion in human milk
- Adverse effects on nursing infant
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Correct volume or salt depletion for hypotension
- Titrate slowly for hepatic or severe renal impairment
- Monitor for worsening heart failure
- Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker
- Potential for precipitating myocardial infarction
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- Recommendations for geriatric use
- Recommendations for hepatic impairment
Overdose Effects
- Manifestations of telmisartan overdose
- Supportive treatment for symptomatic hypotension
- Manifestations of amiodipine overdose
- Monitoring and cardiovascular support for hypotension
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children