Benadip 5 mg+10 mg (Capsule)

Unit Price: ৳ 6.00 (7 x 4: ৳ 168.00)
Strip Price: ৳ 24.00

Medicine Details

Indications

  • Treatment of hypertension

Pharmacology

  • Inhibition of angiotensin-converting enzyme
  • Peripheral arterial vasodilation
  • Reduction in peripheral vascular resistance
  • Lowering of blood pressure
  • Selective inhibition of calcium ion influx
  • Vascular smooth muscle inhibition

Dosage & Administration

  • Effective in once-daily doses of 2.5-10 mg for Amlodipine
  • Effective in doses of 10-80 mg for Benazepril
  • Dose titration guided by clinical effect
  • Recommended initial dose for small, elderly, or hepatically impaired patients is 2.5 mg

Interaction

  • Interactions with diuretics, potassium supplements, potassium-sparing diuretics
  • Safe administration with various medications including anticoagulants, beta blockers, calcium-blocking agents, diuretics, digoxin, and nonsteroidal anti-inflammatory drugs

Contraindications

  • Contraindicated in patients hypersensitive to Benazepril or Amlodipine

Side Effects

  • Mild and transient side effects
  • Discontinuation due to side effects in approximately 4% of patients
  • Common side effects include cough, headache, dizziness, edema, and angioedema
  • Rare side effects include insomnia, nervousness, anxiety, hypokalemia, pharyngitis, etc.

Pregnancy & Lactation

  • Pregnancy Categories C (first trimester) and D (second and third trimesters)
  • Discontinuation recommended when pregnancy is detected
  • Minimal amounts excreted in breast milk

Precautions & Warnings

  • Use with caution in patients with severe renal disease
  • Potential occurrence of hyperkalemia
  • Caution in patients with severe hepatic impairment
  • Consider ACE inhibitor-induced cough in differential diagnosis of cough
  • Consideration in patients undergoing surgery or anesthesia
  • No evidence of carcinogenicity, mutagenicity or impairment of fertility observed

Use in Special Populations

  • Clinical experience not identified differences in responses between the elderly and younger patients
  • Safety and effectiveness not established in pediatric patients

Overdose Effects

  • No human overdoses reported

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Keep below 25°C temperature
  • Away from light and moisture
  • Keep out of reach of children

Related Brands