Benadip 5 mg+10 mg (Capsule)
Unit Price: ৳ 6.00 (7 x 4: ৳ 168.00)
Strip Price: ৳ 24.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate benazepril hydrochloride |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension
Pharmacology
- Inhibition of angiotensin-converting enzyme
- Peripheral arterial vasodilation
- Reduction in peripheral vascular resistance
- Lowering of blood pressure
- Selective inhibition of calcium ion influx
- Vascular smooth muscle inhibition
Dosage & Administration
- Effective in once-daily doses of 2.5-10 mg for Amlodipine
- Effective in doses of 10-80 mg for Benazepril
- Dose titration guided by clinical effect
- Recommended initial dose for small, elderly, or hepatically impaired patients is 2.5 mg
Interaction
- Interactions with diuretics, potassium supplements, potassium-sparing diuretics
- Safe administration with various medications including anticoagulants, beta blockers, calcium-blocking agents, diuretics, digoxin, and nonsteroidal anti-inflammatory drugs
Contraindications
- Contraindicated in patients hypersensitive to Benazepril or Amlodipine
Side Effects
- Mild and transient side effects
- Discontinuation due to side effects in approximately 4% of patients
- Common side effects include cough, headache, dizziness, edema, and angioedema
- Rare side effects include insomnia, nervousness, anxiety, hypokalemia, pharyngitis, etc.
Pregnancy & Lactation
- Pregnancy Categories C (first trimester) and D (second and third trimesters)
- Discontinuation recommended when pregnancy is detected
- Minimal amounts excreted in breast milk
Precautions & Warnings
- Use with caution in patients with severe renal disease
- Potential occurrence of hyperkalemia
- Caution in patients with severe hepatic impairment
- Consider ACE inhibitor-induced cough in differential diagnosis of cough
- Consideration in patients undergoing surgery or anesthesia
- No evidence of carcinogenicity, mutagenicity or impairment of fertility observed
Use in Special Populations
- Clinical experience not identified differences in responses between the elderly and younger patients
- Safety and effectiveness not established in pediatric patients
Overdose Effects
- No human overdoses reported
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 25°C temperature
- Away from light and moisture
- Keep out of reach of children