Cinemet CR 100 mg+25 mg (Tablet (Controlled Release))

Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Levodopa carbidopa cr tablet
Company Aci limited
Also available as
Cinemet cr 200 mg tablet

Indications

  • Idiopathic Parkinson's disease
  • Off-period reduction
  • Motor fluctuations

Description

  • Levodopa metabolic precursor of dopamine
  • Carbidopa dopa decarboxylase inhibitor
  • Blood-brain barrier crossing

Dosage

  • Substitution guideline for conventional levodopa/decarboxylase inhibitors
  • Dosing interval prolongation
  • Titration based on clinical response

Administration

  • Initial recommended dose for different patient groups
  • Titration for therapy start
  • Maintenance dosages and intervals

Interaction

  • Caution with antihypertensive agents
  • Concomitant use with antidepressants
  • Effect on absorption with anticholinergics

Contraindications

  • Sympathomimetic amine contraindication
  • Non-selective MAO inhibitor contraindication
  • Hypersensitivity and narrow-angle glaucoma contraindications

Side Effects

  • Frequency of dyskinesia incidence
  • Various side-effects including nausea, hallucinations, dizziness

Pregnancy & Lactation

  • Insufficient data for harmfulness in pregnancy
  • Possible excretion in human milk

Precautions & Warnings

  • Discontinuation of levodopa monotherapy before therapy start
  • Dyskinesias occurrence and dosage reduction
  • Caution in severe cardiovascular or pulmonary disease

Use in Special Populations

  • Safety and effectiveness in children not established

Therapeutic Class

  • Antiparkinson drugs

Storage Conditions

  • Cool and dry place
  • Protected from light

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