Nokof DS 250 mg/5 ml (Syrup)
100 ml bottle: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Carbocisteine |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Expectoration in upper respiratory inflammation (pharyngitis, laryngitis)
- Expectoration in acute bronchitis
- Expectoration in bronchial asthma
- Expectoration in chronic bronchitis
- Expectoration in bronchiectasis
- Expectoration in pulmonary tuberculosis
- Drainage in chronic sinusitis
- Drainage in otitis media with effusion
Pharmacology
- Reduces viscosity of non-infected secretions in the respiratory tract
- Breaks disulphide bonds in mucus
- Alters local ionic charges affecting mucus viscosity
- Alters composition of mucin secreted by respiratory mucosa
Dosage & Administration
- Initial dosage of 2250 mg daily in divided doses for adults
- Reduced to 1500 mg daily in divided doses for adults
- Normal daily dose of 20 mg/kg body weight in divided doses for children
- 62.5-125 mg 4 times daily for children aged 2-5 years
- 250 mg 3 times daily for children aged 6-12 years
- No established dosage for infants
Interaction
- No hazardous or therapeutically useful interactions reported
Contraindications
- Contraindicated in active peptic ulceration
- Contraindicated in patients with hypersensitivity to the drug
Side Effects
- Gastrointestinal discomfort
- Nausea
- Diarrhoea
- Gastrointestinal bleeding
- Headache
- Skin rash
Pregnancy & Lactation
- Not recommended in first trimester of pregnancy
- No information available on use during lactation
Precautions & Warnings
- Use with caution in patients with recent history of peptic ulcer
- Use with caution in patients with recurrent gastrointestinal bleeding
Therapeutic Class
- Cough expectorants & mucolytics
Storage Conditions
- Keep below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children