Arilol 6.25 mg (Tablet)
Unit Price: ৳ 3.00 (30's pack: ৳ 90.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Carvedilol |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of mild, moderate, or severe heart failure
- Ischemic or cardiomyopathic origin
- Reduction of disease progression
- Conjunction with digitalis, diuretics, and ACE inhibitor
- Cardiovascular death prevention
- Cardiovascular hospitalization prevention
- Adjustment of other heart failure medications
- Use in patients unable to tolerate ACE inhibitor
- Use in patients not receiving digitalis, hydralazine, or nitrate therapy
- Non-selective antagonism of beta-adrenergic receptors
- Alpha-adrenergic antagonistic activity
- Antiproliferative properties
- Scavenger of reactive free oxidant radicals
- Treatment of hypertension
- Treatment of angina pectoris
- Treatment of congestive heart failure
Pharmacology
- Mode of action as a cardiovascular drug
- Non-selective antagonism of beta-adrenergic receptors
- Alpha-adrenergic antagonistic activity
- Antiproliferative properties
- Scavenger of reactive free oxidant radicals
Dosage & Administration
- Initial dose of 12.5 mg once daily for hypertension
- Initial dose of 12.5 mg twice daily for angina pectoris
- Initial dose of 3.125 mg twice daily for heart failure
- Maximum dosage of 50 mg daily for hypertension
- Maximum dosage of 50 mg daily for angina pectoris
- Maximum dosage of 25 mg twice daily for heart failure
Interaction
- Interaction with digoxin
- Interaction with rifampin
- Interaction with warfarin
- Interaction with clonidine
Contraindications
- Decompensated heart failure requiring intravenous inotropic therapy
- Bronchial asthma or related bronchospastic conditions
- Second or third-degree AV block
- Sick sinus syndrome without a permanent pacemaker
- Cardiogenic shock
- Severe bradycardia
Side Effects
- Postural hypotension
- Dizziness
- Headache
- Fatigue
- Gastro-intestinal disturbances
- Bradycardia
- Diminished peripheral circulation
- Peripheral edema
- Painful extremities
- Dry mouth
- Dry eyes
- Eye irritation
- Disturbed vision
- Impotence
- Disturbances of micturition
- Influenza-like symptoms
- Angina
- AV block
- Exacerbation of intermittent claudication or Raynaud's phenomenon
- Allergic skin reactions
- Exacerbation of psoriasis
- Nasal stuffiness
- Wheezing
- Depressed mood
- Sleep disturbances
- Paresthesia
- Changes in liver enzymes
- Thrombocytopenia
- Leukopenia
Pregnancy & Lactation
- Not to be used during breastfeeding
- Not to be used during pregnancy
- Excretion in breast milk
- Crosses the placental barrier
- Safety and efficacy not established in children
Precautions & Warnings
- Caution in hepatic impairment
- Monitoring clinical status in heart failure
- Monitoring renal function
- Monitoring heart failure status
Therapeutic Class
- Alpha adrenoceptor blocking drugs
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Keep below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children