Carved 25 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Carvedilol
Company Biopharma limited
Also available as
Carved 625 mg tablet Carved 125 mg tablet

Title

  • Carvedilol 3.125mg Tablet
  • Carvedilol 6.25mg Tablet
  • Carvedilol 12.5mg Tablet
  • Carvedilol 25mg Tablet

Categories

  • Cardiovascular Medication
  • Hypertension Medication
  • Heart Failure Medication
  • Angina Pectoris Medication

Description

  • Indicated for the treatment of mild, moderate or severe heart failure
  • Also used in hypertension and angina pectoris
  • Has non-selective antagonism of β-adrenergic receptors
  • Exhibits antiproliferative properties and scavenges reactive free oxidant radicals

Dimensions

Various tablet sizes available

Color Options

  • White
  • Off-white

Functions

  • Reduces cardiovascular death and hospitalization
  • Used in conjunction with digitalis, diuretics and ACE inhibitor
  • Blocks β-adrenergic receptors and possesses a-adrenergic antagonistic activity

Materials

  • Active ingredient: Carvedilol
  • Inactive ingredients: may contain hypromellose, lactose monohydrate, microcrystalline cellulose, etc.

Dosage Options

  • 3.125mg tablet
  • 6.25mg tablet
  • 12.5mg tablet
  • 25mg tablet

Administration

  • Initial dose for hypertension: 12.5mg once daily
  • Recommended dose for angina pectoris: 25mg twice daily
  • Initial dose for heart failure: 3.125mg twice daily

Interaction with Digoxin

Increases digoxin levels when taken together

Interaction with Rifampin

Results in a 60% decrease in Cmax and AUC

Warfarin Interaction

Does not alter the in vitro plasma protein binding

Interaction with Clonidine

Potentiates the pressor reaction following sudden withdrawal of treatment with clonidine

Contraindications

  • Decompensated heart failure requiring intravenous inotropic therapy
  • Bronchial asthma or related bronchospastic conditions
  • Second or third-degree AV block
  • Sick sinus syndrome without a permanent pacemaker
  • Cardiogenic shock or severe bradycardia

Side Effects

  • Postural hypotension
  • Dizziness
  • Headache
  • Fatigue
  • Gastro-intestinal disturbances
  • Bradycardia
  • Peripheral oedema
  • Dry mouth
  • Impotence
  • Disturbances of micturition
  • Exacerbation of psoriasis
  • Nasal stuffiness
  • Depressed mood
  • Paresthesia

Pregnancy & Lactation

Not recommended during pregnancy or breastfeeding due to limited safety data

Precautions & Warnings

Use caution in hepatic impairment and monitor clinical status in heart failure patients

Therapeutic Class

  • Alpha adrenoceptor blocking drugs
  • Beta-adrenoceptor blocking drugs
  • Beta-blockers

Storage Conditions

Keep below 30°C, away from light & moisture, and out of the reach of children

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