Dilapress 12.5 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Carvedilol |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Title and Categories
- Dilapress Heart Failure Medication
Dimensions
- Not applicable
Color Options
- Not applicable
Functions
- Treatment of mild, moderate or severe heart failure
- Reduction of cardiovascular death and hospitalization
- Non-selective antagonism of β-adrenergic receptors
- Antiproliferative properties
- Scavenger of reactive free oxidant radicals
- Treatment of hypertension
- Treatment of angina pectoris
- Pharmacological action in congestive heart failure
Materials
- Carvedilol
Technical Specifications
- Dosage: 12.5 mg, 25 mg, 50 mg
- Administration: single or divided doses, increased at intervals of at least 2 weeks
- Maximum daily dose: 50 mg
- Interaction with digoxin, rifampin, warfarin, clonidine
Design Elements
- Not applicable
Usability Features
- Indicated for patients unable to tolerate an ACE inhibitor
- Indicated for patients not receiving digitalis, hydralazine or nitrate therapy
- Not to be used in patients with decompensated heart failure requiring intravenous inotropic therapy, bronchial asthma, second or third-degree AV block, sick sinus syndrome, cardiogenic shock, or severe bradycardia
- Caution in hepatic impairment and heart failure
Other Features
- Pregnancy & Lactation: Should not be used during pregnancy or lactation
- Storage Conditions: Keep below 30°C, away from light & moisture, out of the reach of children
Indications
- Treatment of mild, moderate or severe heart failure of ischemic or cardiomyopathic origin
- Reduction of disease progression evidenced by cardiovascular death, hospitalization, or need to adjust heart failure medications
Pharmacology
- Non-selective antagonism of β-adrenergic receptors
- Antiproliferative properties
- Scavenger of reactive free oxidant radicals
- Used in the treatment of hypertension, angina pectoris, and congestive heart failure
Dosage & Administration
- Hypertension: initially 12.5 mg once daily, increased to 25 mg once daily, maximum 50 mg daily
- Angina pectoris: 12.5 mg twice daily for 2 days, then 25 mg twice daily, maximum 50 mg daily
- Heart failure: initially 3.125 mg twice daily, increased to 6.25 mg, then 12.5 mg, then 25 mg, maximum 25 mg twice daily for patients less than 85 kg, 50 mg twice daily for patients over 85 kg
Interaction
- with Digoxin, Rifampin, Warfarin, Clonidine
Contraindications
- Decompensated heart failure requiring intravenous inotropic therapy
- Bronchial asthma or related bronchospastic conditions
- Second or third-degree AV block
- Sick sinus syndrome
- Cardiogenic shock
- Severe bradycardia
Side Effects
- Postural hypotension
- Dizziness
- Headache
- Fatigue
- Gastro-intestinal disturbances
- Bradycardia
- Peripheral oedema
- Dry mouth
- Impotence
- Influenza-like symptoms
- Angina
- Exacerbation of intermittent claudication
- Allergic skin reactions
- Depressed mood
- Sleep disturbances
- Heart failure
- Changes in liver enzymes
- Thrombocytopenia
- Leukopenia
Pregnancy & Lactation
- Should not be used during breast-feeding
- Safety and efficacy in children have not been established
- Crosses the placental barrier
Precautions & Warnings
- Caution in hepatic impairment and in heart failure
- Monitor clinical status after dose initiation and increase
Therapeutic Class
- Alpha adrenoceptor blocking drugs
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Keep below 30°C, away from light and moisture, out of the reach of children