Rovedilol 6.25 mg (Tablet)

Unit Price: ৳ 4.00 (3 x 10: ৳ 120.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Carvedilol
Company Healthcare pharmaceuticals ltd
Also available as

Indications

  • Mild heart failure treatment
  • Moderate heart failure treatment
  • Severe heart failure treatment
  • Ischemic heart failure treatment
  • Cardiomyopathic origin heart failure treatment
  • Reduction of disease progression
  • Cardiovascular death prevention
  • Hospitalization prevention
  • Medication adjustment need reduction
  • ACE inhibitor intolerance management
  • Digitalis non-receiving patients management
  • Hydralazine or nitrate therapy management

Pharmacology

  • Non-selective antagonism of beta-adrenergic receptors
  • Alpha-adrenergic antagonistic activity
  • Antiproliferative properties
  • Scavenger of free oxidant radicals
  • Treatment of hypertension
  • Treatment of angina pectoris
  • Treatment of congestive heart failure

Dosage & Administration

  • Initial 12.5 mg once daily for hypertension
  • Usual dose of 25 mg once daily for hypertension
  • Maximum 50 mg daily for hypertension
  • Initial 12.5 mg twice daily for angina pectoris
  • Recommended 25 mg twice daily for angina pectoris
  • Initial 3.125 mg twice daily for heart failure
  • Maximum 25 mg twice daily for patients less than 85 kg
  • Maximum 50 mg twice daily for patients over 85 kg

Interaction

  • Digoxin interaction
  • Rifampin interaction
  • Warfarin interaction
  • Clonidine interaction

Contraindications

  • Decompensated heart failure with intravenous inotropic therapy
  • Bronchial asthma or related bronchospastic conditions
  • Second or third-degree AV block
  • Sick sinus syndrome without permanent pacemaker
  • Cardiogenic shock
  • Severe bradycardia

Side Effects

  • Postural hypotension
  • Dizziness
  • Headache
  • Fatigue
  • Gastro-intestinal disturbances
  • Bradycardia
  • Peripheral circulation issues
  • Peripheral edema
  • Dry mouth
  • Eye irritation
  • Impotence
  • Disturbed vision
  • Paresthesia
  • Changes in liver enzymes
  • Thrombocytopenia
  • Leukopenia
  • Allergic skin reactions

Pregnancy & Lactation

  • Not recommended during breastfeeding
  • Safety and efficacy in children not established
  • Not recommended during pregnancy
  • Crosses placental barrier
  • Safety and efficacy in neonates not established

Precautions & Warnings

  • Caution in hepatic impairment
  • Clinical status monitoring after initiation and dose increase
  • Renal function and heart failure assessment before dose increase

Therapeutic Class

  • Alpha adrenoceptor blocking drugs
  • Beta-adrenoceptor blocking drugs
  • Beta-blockers

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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