Cefa-4 1 gm/vial (IM/IV Injection)
1 gm vial: ৳ 550.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefepime hydrochloride |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of moderate to severe pneumonia
- Treatment of febrile neutropenia
- Treatment of uncomplicated and complicated urinary tract infections
- Treatment of uncomplicated skin and skin structure infections
- Treatment of complicated intra-abdominal infections
Pharmacology
- Bactericidal action
- Mode of action similar to other beta-lactam antibiotics
- Disruption of bacterial cell wall synthesis
Dosage & Administration
- Intravenous administration
- Dosage based on infection type and severity
- Administration over approximately 30 minutes
Interaction
- Monitoring renal function with aminoglycosides
- Potential nephrotoxicity with concomitant administration
Contraindications
- Immediate hypersensitivity reactions to cefepime or cephalosporin antibiotics
- Contraindicated in patients with hypersensitivity to penicillin or other betalactum antibiotics
Side Effects
- Immediate hypersensitivity reactions
- Risk of drug-resistant bacteria with inappropriate use
Pregnancy & Lactation
- Pregnancy Category B
- Excretion in human breast milk
- Caution in nursing women
Precautions & Warnings
- Prescribing in absence of proven or suspected bacterial infection
- Prolonged use may result in overgrowth of non-susceptible microorganisms
- Associated with a fall in prothrombin activity
- Caution in individuals with gastrointestinal disease
Use in Special Populations
- Maximum dose for pediatric patients
- Serious adverse events in geriatric patients with renal insufficiency
- No adjustment necessary for patients with impaired hepatic function
- Dose adjustment in patients with impaired renal function
Overdose Effects
- Symptoms of overdose
- Supportive treatment and observation
- Hemodialysis in presence of renal insufficiency
Therapeutic Class
- Fourth generation Cephalosporins
Reconstitution
- Intravenous and intramuscular administration
- Compatibility with various IV infusion fluids and diluents
- Recommended amount of WFI to be added
Storage Conditions
- Expiry date must be respected
- Keep out of reach of children
- Dispensed only with a registered physician's prescription