Fourgen 2 gm/vial (IV Injection)
2 gm vial: ৳ 1,100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefepime hydrochloride |
| Company | Biopharma limited |
| Also available as |
Therapeutic Class
- Fourth generation Cephalosporins
Indications
- Treatment of moderate to severe pneumonia
- Management of febrile neutropenia
- Management of uncomplicated and complicated urinary tract infections
- Treatment of uncomplicated skin and skin structure infections
- Treatment of complicated intra-abdominal infections
Pharmacology
- Bactericidal nature
- Disruption of peptidoglycan layer synthesis in bacterial cell walls
- Mode of action similar to other beta-lactam antibiotics
Dosage & Administration
- Intravenous administration over approximately 30 minutes
- Varied dosage depending on the type and severity of infection
Interaction
- Increased potential of nephrotoxicity with high doses of aminoglycosides
- Nephrotoxicity reported with concomitant administration of cephalosporins and potent diuretics
Contraindications
- Hypersensitivity reactions to cephalosporin antibiotics
- Hypersensitivity reactions to penicillin or other betalactum antibiotics
Side Effects
- Potential hypersensitivity reactions
Pregnancy & Lactation
- Pregnancy Category B
- Excretion in human breast milk in very low concentrations
- Caution advised during administration to nursing women
Precautions & Warnings
- Avoiding use in the absence of a proven or strongly suspected bacterial infection
- Risk of overgrowth of non-susceptible microorganisms with prolonged use
- Association with a fall in prothrombin activity
- Caution advised in individuals with a history of gastrointestinal disease
- Alteration of glucose metabolism and transient elevation of serum potassium with arginine
Use in Special Populations
- Maximum pediatric dose should not exceed recommended adult dose
- Careful dose selection and monitoring in geriatric patients with renal insufficiency
- No adjustment necessary for patients with impaired hepatic function
- Dose adjustment required in patients with impaired renal function
Overdose Effects
- Need for careful observation and supportive treatment
- Recommendation of hemodialysis in the presence of renal insufficiency
Reconstitution
- Intravenous administration compatibility with various IV infusion fluids
- Intramuscular administration compatibility with specific diluents
- Specific volumes of diluent to be added for different vial sizes
Storage Conditions
- Use before the date of expiry
- Keep out of reach of children
- Dispense only on the prescription of a registered physician