Fourgen 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 550.00

Medicine Details

Category Details
Generic Cefepime hydrochloride
Company Biopharma limited
Also available as
Fourgen 2 gm injection Fourgen 500 mg injection

Title

  • Fourgen (Cefepime) Injection

Category

  • Antibiotic
  • Intravenous Medication
  • Pharmaceutical Product

Indications

  • Treatment of pneumonia (moderate to severe)
  • Treatment of febrile neutropenia
  • Treatment of uncomplicated and complicated urinary tract infections
  • Treatment of uncomplicated skin and skin structure infections
  • Treatment of complicated intra-abdominal infections

Pharmacology

  • Bactericidal action
  • Disruption of peptidoglycan synthesis
  • Similar mode of action as penicillins
  • Inhibition of cell wall structural integrity

Dosage & Administration

  • Intravenous administration over approximately 30 minutes
  • Specific dosage for different infections and severities
  • Adjustment of dosage for patients with renal impairment

Interaction

  • Monitor renal function when administered with aminoglycosides
  • Risk of nephrotoxicity with concomitant diuretic administration

Contraindications

  • Immediate hypersensitivity reactions to cephalosporin antibiotics

Side Effects

  • Potential for immediate hypersensitivity reactions

Pregnancy & Lactation

  • Pregnancy Category B
  • Excretion in human breast milk in very low concentrations

Precautions & Warnings

  • Avoid use in the absence of proven or strongly suspected bacterial infection
  • Risk of overgrowth of non-susceptible microorganisms
  • Association with fall in prothrombin activity
  • Caution in patients with gastrointestinal disease
  • Potential impact on glucose metabolism and serum potassium levels

Use in Special Populations

  • Maximum dose for pediatric patients
  • Risk of serious adverse events in geriatric patients with renal insufficiency
  • No adjustment necessary for patients with impaired hepatic function
  • Dose adjustment for patients with impaired renal function
  • Supportive treatment for overdose

Overdose Effects

  • Symptoms include encephalopathy, myoclonus, seizures
  • Hemodialysis recommended in the presence of renal insufficiency

Therapeutic Class

  • Fourth generation Cephalosporins

Reconstitution

  • Specific instructions for intravenous and intramuscular reconstitution
  • Compatibility with various intravenous infusion fluids and diluents

Storage Conditions

  • Do not use after expiry date
  • Keep out of reach of children
  • Dispense only on prescription

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