Tetracef 2 gm/vial (IV Injection)
2 gm vial: ৳ 1,100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefepime hydrochloride |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Treats moderate to severe pneumonia
- Effective against febrile neutropenia
- Manages uncomplicated and complicated urinary tract infections
- Treats uncomplicated skin and skin structure infections
- Used in combination for complicated intra-abdominal infections
Pharmacology
- Bactericidal
- Disrupts synthesis of bacterial cell walls
- Disrupts peptidoglycan layer of cell walls
- Acts on penicillin binding proteins (PBPs)
Dosage & Administration
- Administered intravenously over 30 minutes
- Specific dosages for different infections
- IV or IM route of administration
- Duration of treatment for each infection
Interaction
- Monitoring required with high doses of aminoglycosides
- Potential nephrotoxicity and ototoxicity with aminoglycosides
- Nephrotoxicity with concomitant use of potent diuretics
Contraindications
- Immediate hypersensitivity reactions to cephalosporins, penicillin, or beta-lactam antibiotics
Side Effects
- Potential for immediate hypersensitivity reactions
Pregnancy & Lactation
- Pregnancy Category B
- Excreted in very low concentrations in breast milk
Precautions & Warnings
- Avoid prescribing in absence of bacterial infection
- Caution with prolonged use to prevent overgrowth of non-susceptible microorganisms
- Association with fall in prothrombin activity
- Caution in patients with history of gastrointestinal disease
Use in Special Populations
- Maximum dose for pediatric patients
- Caution in geriatric patients with renal insufficiency
- No dosage adjustment for impaired hepatic function
- Dosage adjustment for impaired renal function
Overdose Effects
- Careful observation and supportive treatment
- Recommendation for hemodialysis in presence of renal insufficiency
- Symptoms of overdose
Therapeutic Class
Fourth generation Cephalosporins
Reconstitution
- Injection directly into the vein over 3-5 minutes
- Compatibility with various IV infusion fluids
- Compatibility with Intramuscular diluents
- Specific reconstitution details for different vial sizes
Storage Conditions
Do not use later than the expiration date, keep out of reach of children