Lesero 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 115.00

Medicine Details

Category Details
Generic Ceftazidime pentahydrate
Company Ziska pharmaceuticals ltd
Also available as
Lesero 250 mg injection Lesero 1 gm injection

Indications

  • Lower Respiratory Tract Infections
  • Skin and Skin Structure Infections
  • Urinary Tract Infections
  • Bacterial Septicemia
  • Bone and Joint Infections
  • Gynecologic Infections
  • Intraabdominal Infections
  • Central Nervous System Infections

Pharmacology

  • Bactericidal Action
  • Inhibition of Cell-wall Synthesis
  • Susceptibility to Gram-negative Organisms
  • Activity Against Gram-positive Organisms
  • Stability to Beta-lactamases

Dosage

  • Usual Adult Dosage: 1 gram every 8-12 hours
  • Variability Based on Infection Severity and Patient Condition
  • Specific Dosage Ranges for Urinary Tract Infections and Severe Infections
  • Elderly Dosage Limitation
  • Customized Dosage for Infants, Children, and Neonates

Administration

  • Intravenous or Deep IM Injection
  • Reconstitution with Sterile Water for Injection

Contraindications

  • Hypersensitivity to Ceftazidime or Cephalosporins

Side Effects

  • Local Reactions Following IV Injection
  • Allergic and Gastrointestinal Reactions
  • Hypersensitivity Reactions
  • Gastrointestinal Symptoms
  • Central Nervous System Reactions

Pregnancy & Lactation

  • Limited Studies in Pregnant Women
  • Use During Pregnancy Only if Clearly Needed
  • Excretion in Low Concentrations in Human Milk
  • Undetermined Safety for Nursing Infants

Precautions & Warnings

  • Reduced Dosage for Renal Insufficiency
  • Caution in Patients with Gastrointestinal Disease
  • Dosage Adjustment for Peritoneal Dialysis
  • No Dosage Adjustment for Hepatic Dysfunction

Use in Special Populations

  • Dosage Reduction for Impaired Renal Function
  • Usage in Peritoneal Dialysis and CAPD
  • No Dosage Adjustment for Hepatic Dysfunction

Overdose Effects

  • Observation and Supportive Treatment for Overdose
  • Reported Reactions: Seizure Activity, Encephalopathy, Coma

Therapeutic Class

  • Third Generation Cephalosporins

Reconstitution

  • Specific Amount of Sterile Water for Injection per Administration

Storage Conditions

  • Store Below 25°C
  • Protection from Light and Moisture
  • Reconstituted Solution Stability up to 24 hours if Stored Between 2°C-8°C

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