Camlosart 5 mg+40 mg (Tablet)
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate olmesartan medoxomil |
Company | Square pharmaceuticals plc |
Also available as |
Indications
- Treatment of hypertension alone or with other antihypertensive agents
- Lowering blood pressure
- Initial therapy for patients likely to need multiple antihypertensive agents
Pharmacology
- Amlodipine as a dihydropyridine calcium channel blocker
- Greater effect on vascular smooth muscle cells than on cardiac muscle cells
- Peripheral arterial vasodilator
- Olmesartan Medoxomil as angiotensin II receptor antagonist
- Blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II
Dosage & Administration
- Substitute individually titrated components
- Initiate therapy with 5/20 mg once daily
- Titrate up to a maximum of 10/40 mg once daily
- Recommended starting dose of Amlodipine is 2.5 mg in patients 75 years
- Not recommended for patients >75 years old
Interaction
- Antihypertensive effect may be attenuated by NSAIDs including selective COX-2 inhibitors
- Close monitoring of blood pressure, renal function, and electrolytes required
Contraindications
- Contraindicated with Aliskiren in patients with diabetes
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Potential for intestinal problems
Pregnancy & Lactation
- Pregnancy Category D
- Not to be used in 2nd and 3rd trimester
- Discontinue if pregnancy is detected
- Unknown excretion in human milk
- Potential adverse effects on nursing infant
Precautions & Warnings
- Use with caution in volume- or salt-depleted patients
- Risk of hypotension, vasodilation, and angina in specific patient groups
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in geriatric use
- No studies in patients with renal impairment
- Not recommended for hepatically impaired patients
Overdose Effects
- No information on overdosage in humans
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Store below 30°C
- Keep away from light
- Keep out of the reach of children