Cephalen 250 mg (Capsule)

Unit Price: ৳ 6.88 (10 x 10: ৳ 688.00)

Strip Price: ৳ 68.80

Medicine Details

Category	Details
Generic	Cephalexin
Company	Beximco pharmaceuticals ltd
Also available as	Cephalen 125 mg suspension Cephalen 500 mg capsule

Title

Cephalen

Description

Cephalen is a first generation cephalosporin indicated for the treatment of respiratory tract infections, genito-urinary tract infections, skin and soft tissue infections, ear, nose and throat infections, and bone infections caused by susceptible organisms.

Indication

Treatment of respiratory tract infections
Treatment of genito-urinary tract infections
Treatment of skin and soft tissue infections
Treatment of ear, nose and throat infections
Treatment of bone infections

Pharmacology

Cephalexin is a semisynthetic analogue of Cephalosporin C, active by mouth, that kills bacteria by interfering in the synthesis of the bacterial cell wall, weakening the cell wall and causing the bacterial cell to rupture.

DosageAndAdministration

Adult:
- Usual dose: 250 mg to 500 mg every 6 hours
- For skin and soft tissue infections and streptococcal pharyngitis in patients over 15 years of age: 500 mg every 12 hours
- In severe infections: Up to 3 g to 6 g daily
Children:
- RecommendedDose:
  - 10 kg (22 lbs): 62.5 mg to 125 mg qid or 125 mg to 250 mg bid
  - 20 kg (44 lbs): 125 mg to 250 mg qid or 250 mg to 500 mg bid
  - 40 kg (88 lbs): 250 mg to 500 mg qid or 500 mg to 1 g bid
- SpecificConditions:
  - Streptococcal pharyngitis: Total daily dose may be divided and administered every 12 hours
  - Otitis media: 75-100 mg/kg/day in four divided doses may be required
  - β-haemolytic streptococcal infections: Therapeutic dosage should be given for at least 10 days

Contraindications

Contraindicated in patients with known hypersensitivity to the cephalosporin group of antibiotics

SideEffects

Nausea
Vomiting
Diarrhoea
Abdominal discomfort
Pseudomembranous colitis
Skin rash
Angioedema
Rise in serum aminotransferases
Eosinophilia
Neutropenia
Superinfection with resistant microorganisms

PregnancyAndLactation

PregnancyCategory: Category B
UsageDuringPregnancy: May be used when considered essential
UsageDuringLactation: Caution should be taken when administered to nursing mothers

PrecautionsAndWarnings

RenalImpairment: Cefalexin should be given with caution in patients with renal impairment
GlucoseReaction: The urine of patients receiving Cefalexin may give a false positive reaction for glucose with copper reduction reagent
CoombsTest: Positive results to Coombs’ test have been reported