Navalexin 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephalexin
Company Navana pharmaceuticals ltd
Also available as
Navalexin 250 mg capsule Navalexin 500 mg capsule

Indications

  • Respiratory tract infections: Acute and chronic bronchitis and infected bronchiectasis
  • Genito-urinary tract infections: Acute and chronic nephritis, cystitis, urethritis and prostatitis
  • Skin and soft tissue infections: Caused by staphylococci and/or streptococci
  • Ear, Nose and Throat infections: Otitis media, mastoiditis, sinusitis, follicular tonsillitis and pharyngitis
  • Bone infections: Caused by staphylococci and/or P. mirabilis

Pharmacology

Cephalexin is a semisynthetic analogue of Cephalosporin C. It kills bacteria by interfering in the synthesis of the bacterial cell wall.

Dosage & Administration

  • Adult:
    • Usual dose is 250 mg to 500 mg every 6 hours
    • For skin and soft tissue infections, streptococcal pharyngitis and uncomplicated cystitis, in patients over 15 years of age: 500 mg of the drug may be administered every 12 hours
    • In severe or deep-seated infections, the dose can be increased up to 3 g to 6 g daily
  • Children: The dosage range is 25-100 mg/kg/day in divided doses to a maximum of 4 g daily

Contraindications

Cephalen is contraindicated in patients with known hypersensitivity to the cephalosporin group of antibiotics.

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal discomfort
  • Pseudomembranous colitis may appear either during or after antibiotic treatment
  • Skin rash
  • Angioedema
  • Rise in serum aminotransferases
  • Eosinophilia
  • Neutropenia
  • Superinfection with resistant microorganisms, particularly candida may follow the treatment

Pregnancy & Lactation

Pregnancy Category B. Cefalexin may be used during pregnancy when it is considered essential. Cefalexin is found in the milk of nursing mothers, hence caution should be taken when it is administered to nursing mothers.

Precautions & Warnings

  • Cefalexin should be given with caution in patients with renal impairment
  • Careful clinical observation should be made because safe dosage may be lower than the usually recommended
  • The urine of patients receiving Cefalexin may give a false positive reaction for glucose with copper reduction reagent
  • Positive results to Coombs’ test have been reported

Therapeutic Class

First generation Cephalosporins

Storage Conditions

Should be stored in a cool and dry place

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