Durazol 400 mg (Chewable Tablet)
Unit Price: ৳ 4.00 (50's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Millat pharmaceuticals ltd |
| Also available as |
Indications
- Hookworm (Ancylostoma, Necator)
- Roundworm (Ascaris)
- Threadworm (Enterobius)
- Whipworm (Trichuris)
- Strongyloides
- Tapeworm
- Opisthorchi
- Hydatid
Description
Benzimidazole anthelmintic
Principal mode of action
Inhibitory effect on tubulin polymerization
Pharmacology
Broad spectrum anthelmintic
Mechanism of action
Blocks glucose uptake in susceptible helminths
Metabolism
Extensively metabolized, probably in the liver
Half-life
Plasma half-life of about 8.5 hrs
Dosage & Administration
- Adults & children over 2 years: 400 mg as a single dose
- Children of 1-2 years: Recommended dose of 200 mg
- In Hydatid disease: Dose of 400 mg twice daily for patients weighing over 60 kg
Interaction
No reported interactions involving Durazol
Contraindications
- Neonates
- Pregnant woman
- Concurrent disease
Side Effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Reversible alopecia
- Rash
- Fever
- Blood disorders
- Allergic shock
- Convulsion
- Meningism
Pregnancy & Lactation
US FDA Pregnancy category of Albendazole is C
Precautions & Warnings
- Blood counts and liver function tests before treatment and twice during each cycle
- Excluding pregnancy before starting treatment
- Constant medical supervision in the treatment of Echinococcosis
Therapeutic Class
Anthelmintic
Storage Conditions
Keep in a dry place, away from light and heat