Aristophen 1% (Ophthalmic Ointment)

3 gm tube: ৳ 8.39

Medicine Details

Category Details
Generic Chloramphenicol ophthalmic
Company Aristopharma ltd
Also available as
Aristophen 05 eye drop

Indications

  • Treatment of ocular infections involving the conjunctiva and/or cornea
  • Infections caused by Aristophen-susceptible organisms
  • Infections caused by specific bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, E.coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species

Pharmacology

  • Broad-spectrum bacteriostatic antibiotic
  • Inhibition of bacterial protein synthesis
  • Interference with transfer of activated amino acids from soluble RNA to ribosomes

Dosage & Administration

  • Instill 1 or 2 drops in the conjunctival sac 4-6 times per day
  • Initial treatment frequency of 4-6 times per day for 72 hours
  • Subsequent treatment frequency of every 4 hours
  • Approximately 7 days treatment duration
  • Maximum treatment duration of 3 weeks without re-evaluation by the physician

Interaction

  • Inhibition of Chymotrypsin if given simultaneously with Aristophen

Contraindications

  • Contraindicated in individuals with hypersensitivity to Chloramphenicol or any ingredients of the preparation

Side Effects

  • Burning sensation
  • Stinging
  • Conjunctival hyperemia
  • Blood dyscrasia
  • Allergic or inflammatory reactions
  • Vesicular and maculopapular dermatitis

Pregnancy & Lactation

  • Safety not established for use in pregnancy and lactation
  • Use only when considered essential by physicians

Precautions & Warnings

  • Avoid use for minor infections or prophylaxis
  • Avoid repeated and prolonged treatment
  • Risk of blood dyscrasias
  • Risk of granulocytopenia, thrombocytopenia, and moderate anemia after prolonged use

Overdose Effects

  • Unlikely to cause toxicity due to low antibiotic content

Therapeutic Class

  • Ear Anti-Infectives & Antiseptics
  • Eye Anti-Infectives & Antiseptics
  • Macrolides

Storage Conditions

  • Store in a cool (between 2°C-8°C) and dry place
  • Protect from light
  • Keep out of reach of children
  • Do not touch the dropper tip to the surface to prevent contamination
  • Do not use after 30 days of the first opening

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