Cip 0.3% (Ophthalmic Ointment)

3 gm tube: ৳ 32.00

Medicine Details

Category	Details
Generic	Ciprofloxacin ophthalmic
Company	Asiatic laboratories ltd
Also available as	Cip 03 eye drop

Indications

Treatment of corneal ulcers
Treatment of conjunctivitis
Treatment of blepharitis
Bacterial susceptibility

Composition

Active substance: Ciprofloxacin Hydrochloride BP equivalent to Ciprofloxacin 3 mg per ml
Preservative: Benzalkonium Chloride 0.06 mg per ml

Pharmacology

In vitro activity against a wide range of Gram-negative and Gram-positive organisms
Bactericidal action
Inhibition of DNA gyrase (topoisomerase)

Dosage & Administration

Corneal ulcers: specific instillation regimen
Bacterial conjunctivitis/blepharitis: specific instillation regimen
Pediatric use safety information

Interaction

Potential drug interactions
Elevation of plasma concentrations of theophylline
Interference with caffeine metabolism
Enhancement of effects of oral anticoagulant warfarin
Transient elevations in serum creatinine with concurrent cyclosporine administration

Contraindications

Hypersensitivity to Ciprofloxacin
Hypersensitivity to other quinolones

Side Effects

Local burning or discomfort
Precipitates in corneal ulcer studies
Lid margin crusting
Foreign body sensation
Itching
Conjunctival hyperemia
Bad taste following instillation
Various ocular adverse reactions

Pregnancy & Lactation

Lack of adequate and well-controlled studies in pregnant women
Use during pregnancy based on risk-benefit assessment

Precautions & Warnings

Potential overgrowth of non-susceptible organisms
Super-infection
Hypersensitivity reactions
Skin rash as a sign for discontinuation

Overdose Effects

Procedure for topical overdose management

Therapeutic Class

Aural Anti-bacterial preparations
Ophthalmic antibacterial drugs

Storage Conditions

Room temperature storage
Protection from light
Use within one month after opening

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