Cip 0.3% (Ophthalmic Ointment)

Indications

• Treatment of corneal ulcers
• Treatment of conjunctivitis
• Treatment of blepharitis
• Bacterial susceptibility

Composition

• Active substance: Ciprofloxacin Hydrochloride BP equivalent to Ciprofloxacin 3 mg per ml
• Preservative: Benzalkonium Chloride 0.06 mg per ml

Pharmacology

• In vitro activity against a wide range of Gram-negative and Gram-positive organisms
• Bactericidal action
• Inhibition of DNA gyrase (topoisomerase)

Dosage & Administration

• Corneal ulcers: specific instillation regimen
• Bacterial conjunctivitis/blepharitis: specific instillation regimen
• Pediatric use safety information

Interaction

• Potential drug interactions
• Elevation of plasma concentrations of theophylline
• Interference with caffeine metabolism
• Enhancement of effects of oral anticoagulant warfarin
• Transient elevations in serum creatinine with concurrent cyclosporine administration

Contraindications

• Hypersensitivity to Ciprofloxacin
• Hypersensitivity to other quinolones

Side Effects

• Local burning or discomfort
• Precipitates in corneal ulcer studies
• Lid margin crusting
• Foreign body sensation
• Itching
• Conjunctival hyperemia
• Bad taste following instillation
• Various ocular adverse reactions

Pregnancy & Lactation

• Lack of adequate and well-controlled studies in pregnant women
• Use during pregnancy based on risk-benefit assessment

Precautions & Warnings

• Potential overgrowth of non-susceptible organisms
• Super-infection
• Hypersensitivity reactions
• Skin rash as a sign for discontinuation

Overdose Effects

• Procedure for topical overdose management

Therapeutic Class

• Aural Anti-bacterial preparations
• Ophthalmic antibacterial drugs

Storage Conditions

• Room temperature storage
• Protection from light
• Use within one month after opening

Related Brands

• Cipro-C 0.3% (Ophthalmic Solution) - chemist-laboratories-ltd