D-Best 40000 IU (Capsule)

Unit Price: ৳ 35.00 (1 x 10: ৳ 350.00)
Strip Price: ৳ 350.00

Medicine Details

Category Details
Generic Cholecalciferol vitamin d3
Company Pacific pharmaceuticals ltd
Also available as
D best 200000 iu injectable solution oral im D best 20000 iu capsule

Indications

  • Prevention of rickets
  • Treatment of osteoporosis
  • Prevention of osteomalacia
  • Vitamin D3 deficiency
  • Immunity boost
  • Pre-eclampsia prevention during pregnancy

Pharmacology

  • Calcitriol binding to Vitamin D receptors
  • Absorption in small intestine
  • Metabolism in liver and kidney
  • Half-life of 50 days
  • Storage in fat and muscle
  • Elimination via faeces and urine

Dosage & Administration

  • 40000 IU once weekly for 7 weeks for adults
  • 1000 IU daily for film-coated tablet
  • Chewable tablets available
  • Syrup dosage for different age groups
  • Injection dosage for different age groups
  • Dosage for pregnant women

Interaction

  • Interference with Magnesium containing Antacids
  • Interference with certain Diuretics
  • Interference with Corticosteroids
  • Increased need due to Prednisolone use

Contraindications

  • Hypercalcaemia-associated diseases
  • Known hypersensitivity
  • Evidence of Vitamin D3 toxicity

Side Effects

  • Anorexia
  • Nausea & vomiting
  • Headache
  • Polyuria
  • Vertigo
  • Raised calcium and phosphate concentrations

Pregnancy & Lactation

  • Safe use up to 4000 IU during pregnancy
  • Excretion in breast milk
  • Potential overdose in breast-fed infants

Precautions & Warnings

  • Plasma-calcium concentration monitoring
  • Consultation for patients with renal impairment
  • Consultation for patients with liver or kidney disease
  • Consultation for patients with primary hyperthyroidism
  • Consultation for patients with granulomatous disease

Use in Special Populations

  • Safety & efficacy not established for children under 12 years

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Keep below 30°C
  • Protected from light & moisture
  • Keep out of the reach of children

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