D-Best 40000 IU (Capsule)
Unit Price: ৳ 35.00 (1 x 10: ৳ 350.00)
Strip Price: ৳ 350.00
Medicine Details
Category | Details |
---|---|
Generic | Cholecalciferol vitamin d3 |
Company | Pacific pharmaceuticals ltd |
Also available as |
Indications
- Prevention of rickets
- Treatment of osteoporosis
- Prevention of osteomalacia
- Vitamin D3 deficiency
- Immunity boost
- Pre-eclampsia prevention during pregnancy
Pharmacology
- Calcitriol binding to Vitamin D receptors
- Absorption in small intestine
- Metabolism in liver and kidney
- Half-life of 50 days
- Storage in fat and muscle
- Elimination via faeces and urine
Dosage & Administration
- 40000 IU once weekly for 7 weeks for adults
- 1000 IU daily for film-coated tablet
- Chewable tablets available
- Syrup dosage for different age groups
- Injection dosage for different age groups
- Dosage for pregnant women
Interaction
- Interference with Magnesium containing Antacids
- Interference with certain Diuretics
- Interference with Corticosteroids
- Increased need due to Prednisolone use
Contraindications
- Hypercalcaemia-associated diseases
- Known hypersensitivity
- Evidence of Vitamin D3 toxicity
Side Effects
- Anorexia
- Nausea & vomiting
- Headache
- Polyuria
- Vertigo
- Raised calcium and phosphate concentrations
Pregnancy & Lactation
- Safe use up to 4000 IU during pregnancy
- Excretion in breast milk
- Potential overdose in breast-fed infants
Precautions & Warnings
- Plasma-calcium concentration monitoring
- Consultation for patients with renal impairment
- Consultation for patients with liver or kidney disease
- Consultation for patients with primary hyperthyroidism
- Consultation for patients with granulomatous disease
Use in Special Populations
- Safety & efficacy not established for children under 12 years
Overdose Effects
- Hypervitaminosis D
Therapeutic Class
- Vitamin in bone formation
- Vitamin-D preparations
Storage Conditions
- Keep below 30°C
- Protected from light & moisture
- Keep out of the reach of children