Refla 6 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Jenphar bangladesh ltd |
| Also available as |
Title
Refla
Categories
- Medicine
- Pharmaceutical
Description
Refla is a glucocorticoid used for indications such as anaphylaxis, asthma, severe hypersensitivity reactions, rheumatoid arthritis, juvenile chronic arthritis, polymyalgia rheumatica, systemic lupus erythematosus, dermatomyositis, mixed connective tissue disease, and many more.
DosageAndAdministration
- Adults:
- Up to 120 mg/day for acute disorders
- Maintenance doses range from 3-18 mg/day for most conditions
- Children:
- Usual maintenance dose for juvenile chronic arthritis is between 0.25-1.0 mg/kg/day
- Withdrawal: Gradual dose reduction for patients receiving more than physiological doses for greater than 3 weeks
Pharmacology
Deflazacort provides anti-inflammatory action by inhibiting Phospholipase A2 enzyme and decreases the release of certain chemicals in the immune system.
Interaction
Metabolized in the liver, maintenance dose may need adjustment with liver enzyme inducers or inhibitors
Contraindications
- Hypersensitivity to any of the ingredients
- Patients receiving live virus immunization
SideEffects
- GI disturbances
- Musculoskeletal issues
- Endocrine problems
- Neuropsychiatric effects
- Ophthalmic complications
- Fluid and electrolyte disturbances
- Susceptibility to infection
PregnancyAndLactation
- Pregnancy: Corticosteroids may increase the risk of intrauterine growth retardation
- Lactation: Excreted in breast milk, likelihood of systemic effects in the infant with higher doses
PrecautionsAndWarnings
- ConditionsRequireCaution:
- Cardiac disease or congestive heart failure
- Gastritis or oesophagitis
- Diabetes mellitus or family history
- Emotional instability or psychotic tendency
- SpecialPopulations:
- Hepatic Impairment
- Renal Impairment
- Elderly
TherapeuticClass
- Glucocorticoids
StorageConditions
Store in a cool (below 25°C) and dry place, protected from light & moisture, keep out of reach of children