Ostoref DX 600 mg+400 IU (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Coral calcium vitamin d3
Company Opsonin pharma ltd
Also available as
Ostoref d 500 mg tablet

Indications

  • Treatment & prevention of Osteoporosis
  • Treatment & prevention of Osteomalacia
  • Treatment & prevention of Tetany
  • Treatment & prevention of Hypoparathyroidism
  • Treatment & prevention of Disorders of osteogenesis
  • Supplement for inadequate intake of Calcium in childhood diet
  • Supplement for rickets
  • Supplement for pregnancy & lactation
  • Supplement for elderly patients
  • Supplement for pancreatitis
  • Phosphate binder in chronic renal failure

Composition

  • Each tablet contains Calcium Carbonate USP 1250 mg (Coral source) equivalent to 500 mg of elemental Calcium & Vitamin D USP 200 IU
  • Each DX tablet contains Calcium Carbonate USP 1500 mg (Coral source) equivalent to 600 mg of elemental Calcium & Vitamin D USP 400 IU
  • Each effervescent tablet contains Calcium Carbonate (Coral source) USP 1500 mg equivalent to 600 mg of elemental Calcium and Vitamin D3 400 IU as Cholecalciferol USP

Pharmacology

  • Adequate Calcium in the blood is vital for bodily functions
  • Calcium is useful for the prevention and treatment of Osteoporosis
  • Vitamin D is essential for healthy bones and aids in Calcium absorption from the GI tract
  • Vitamin D stimulates bone formation
  • Calcium and vitamin D have synergistic effects on bone growth and in Osteoporosis and fracture prevention
  • Coral Calcium has a chemical structure similar to human bone
  • Coral Calcium ensures better absorption
  • Vitamin D3 aids in the absorption of Calcium and helps maintain Calcium balance in the body

Dosage & Administration

  • One tablet once or twice daily with plenty of water or as directed by the physician
  • Taking in full stomach ensures better absorption
  • Dissolve 1 effervescent tablet in a glass of water to drink orally
  • Stir the solution with a spoon before drinking
  • Taking in full stomach ensures better absorption

Interaction

  • Thiazide diuretics reduce the urinary excretion of calcium
  • Systemic corticosteroids reduce calcium absorption
  • Simultaneous treatment with ion exchange resins and laxatives may reduce the gastrointestinal absorption of vitamin D
  • Calcium carbonate may interfere with the absorption of concomitantly administered tetracycline preparations
  • Hypercalcaemia may increase the toxicity of cardiac glycosides during treatment with calcium and vitamin D
  • Bisphosphonate or sodium fluoride usage affects the absorption of Ostoref DX
  • Oxalic acid and phytic acid may inhibit calcium absorption

Contraindications

  • Hypercalcemia and hyperparathyroidism
  • Hypercalciuria and nephrolithiasis
  • Hypersensitivity to the component of this preparation
  • Severe renal insufficiencies
  • Concomitant digoxin therapy

Side Effects

  • GI tract irritation
  • Constipation
  • Hypercalcemia (rare)
  • Allergic reactions
  • Irregular heartbeats
  • Nausea
  • Vomiting
  • Decreased appetite
  • Dry mouth
  • Drowsiness
  • Skin rash from Vitamin D supplements

Pregnancy & Lactation

  • Daily intake should not exceed 1500 mg calcium and 600 IU cholecalciferol
  • Overdoses of calcium and vitamin D should be avoided during pregnancy
  • No indications that vitamin D at therapeutic doses is teratogenic in humans
  • Elemental Calcium & Vitamin D3 tablet can be used during pregnancy and breast-feeding

Precautions & Warnings

  • Serum calcium levels and renal function should be monitored during long-term treatment
  • Serum calcium levels and urinary calcium excretion must be monitored in immobilized patients with osteoporosis
  • Vitamin D should be used with caution in patients with impaired renal function
  • Calcium and vitamin D3 tablet should be prescribed with caution to patients suffering from sarcoidosis
  • Consideration of soft tissue calcification risk in patients with severe renal insufficiency

Overdose Effects

  • Hypervitaminosis D and hypercalcaemia
  • Symptoms of hypercalcaemia may include anorexia, thirst, nausea, vomiting, constipation, abdominal pain, muscle weakness, fatigue, mental disturbances, polydipsia, polyuria, bone pain, nephrocalcinosis, nephrolithiasis, and in severe cases, cardiac arrhythmias

Therapeutic Class

  • Specific mineral & vitamin combined preparations

Storage Conditions

  • Store at temperature of below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

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