Elazol 50 mg (Tablet)
Unit Price: ৳ 50.00 (2 x 4: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Renata limited |
| Also available as |
Indications
- Invasive aspergillosis
- Candidemia
- Disseminated candidiasis
- Esophageal candidiasis
- Serious infections caused by Scedosporium apiospermum
- Intolerance/refractory to other therapy
Pharmacology
- Triazole antifungal medication
- Binds and inhibits ergosterol synthesis
- Inhibits CYP450-dependent 14-alpha sterol demethylase
Dosage & Administration
- Oral administration
- Loading dose based on body weight
- Maintenance dose after initial 24 hours
- Injection for specific infections
Interaction
- CYP3A4, CYP2C9, and CYP2C19 inhibitors/inducers adjustment
- Increased concentrations/activity of CYP3A4, CYP2C9, and CYP2C19 substrates
- Increase in maintenance dosage with specific drug co-administration
Contraindications
- Hypersensitivity to voriconazole or components
- Co-administration with specific drugs due to risk of adverse reactions or loss of efficacy
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- Limited studies in pregnant women
- Use only if potential benefit justifies potential risk to fetus
Precautions & Warnings
- Careful assessment for long-term exposure
- Reported risk of squamous cell carcinoma with long-term treatment
Use in Special Populations
- Efficacy not established for children under 12 years of age
Overdose Effects
- No available data on overdose effects
Therapeutic Class
- Other antifungal preparations
Reconstitution
- Instructions for reconstituting suspension
- Storage and discard guidelines for reconstituted suspension
Storage Conditions
- Keep out of reach of children
- Store in a dry place below 25°C
- Specific storage instructions for powder for suspension