Amlovas VS 5 mg+160 mg (Tablet)
Unit Price: ৳ 16.06 (3 x 10: ৳ 481.80)
Strip Price: ৳ 160.60
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate valsartan |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension
Pharmacology
- Dihydropyridine calcium channel blocker
- Inhibits transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle
- Blocks vasoconstrictor and aldosterone-secreting effects of Angiotensin II
- Effective in lowering blood pressure
- Reduces peripheral resistance
Dosage & Administration
- Effective doses for Amlodipine: 2.5 mg - 10 mg
- Effective doses for Valsartan: 80 mg-320 mg
- Antihypertensive effects increase with increasing doses
- Majority of antihypertensive effect attained within 2 weeks
- Dosage can be increased to a maximum of 10/320 mg once daily if needed
- May be administered with or without food
- May be administered with other antihypertensive agents
- Lower initial dosage recommended for elderly patients
- No initial dosage adjustment required for patients with mild or moderate renal impairment
- Titrate slowly in patients with severe renal impairment
- No initial dosage adjustment required for patients with mild or moderate liver insufficiency
- Titrate slowly in patients with hepatic impairment
Interaction
- No drug interaction studies conducted for Amlodipine and Valsartan combination
Contraindications
- Contraindicated in patients hypersensitive to any component
Side Effects
- Mild and transient side effects
- Common side effects include peripheral edema, nasal congestion, sore throat, discomfort when swallowing, upper respiratory tract infection, dizziness
Pregnancy & Lactation
- Pregnancy Category D
- Not known if excreted in human milk
- Consider discontinuing nursing or drug, weighing importance to the mother
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Assess for hypotension
- Warn patients with severe obstructive coronary artery disease about the risk of myocardial infarction or increased angina
- Titrate slowly in patients with impaired hepatic or severely impaired renal function
Use in Special Populations
- Safety and effectiveness in paediatric patients not established
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Store below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children