Backtone 5 mg (Tablet)
Unit Price: ৳ 5.50 (5 x 10: ৳ 275.00)
Strip Price: ৳ 55.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Baclofen |
| Company | Pharmacil limited |
| Also available as |
Indications
- spasticity resulting from multiple sclerosis
- flexor spasms and concomitant pain, clonus and muscular rigidity
- skeletal muscle spasm resulting from rheumatic disorders
- spinal cord injuries and other spinal cord diseases
- cerebrovascular accidents or neoplastic or degenerative brain disease
Pharmacology
- inhibits both monosynaptic and polysynaptic reflexes at the spinal level
- stimulates the GABA receptors
- inhibits the release of glutamate and aspartate
- exerts antinociceptive effect
- may produce CNS depression
Dosage & Administration
- 5 mg 3 times daily for adults & children over 10 years
- gradually increased dosage; max. 100 mg daily
- Treatment is usually started with 2.5 mg (2.5 ml) given 4 times daily for children <10 years
- Daily maintenance dose varied based on age
Interaction
- Increased sedation may occur if taken with agents acting on the central nervous system, alcohol or synthetic opiates
- Combined treatment with antihypertensives likely to increase the fall in blood pressure
- Concomitant administration with tricyclic antidepressants may potentiate the pharmacological effects
- Concurrent use with MAO inhibitors may result in increased CNS depressant effects
- Caution should be exercised when administering with magnesium sulphate or other neuromuscular blocking agents
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- transient drowsiness
- daytime sedation
- dizziness
- weakness
- fatigue
- Various CNS effects
- Cardiovascular effects
- Gastrointestinal effects
- Genitourinary effects
- Other miscellaneous effects
Pregnancy & Lactation
- Pregnancy category B3
- Safe use during pregnancy not established
- Crosses the placental barrier
- Excreted in breast milk
Precautions & Warnings
- Lower doses for patients with impaired renal function or undergoing chronic haemodialysis
- Cautious treatment for patients with psychotic disorders, schizophrenia, depressive or manic disorders
- Caution in patients with epilepsy and muscle spasticity
- Use with caution in patients with peptic ulcers, cerebrovascular diseases, or hepatic, renal or respiratory failure
- Careful monitoring of respiratory and cardiovascular function is essential
- Neurogenic disturbances affecting bladder emptying may improve
- Not significantly beneficial for patients with stroke
- Appropriate laboratory tests should be performed in certain patients
Overdose Effects
- Gastric lavage is important in case of severe overdose
Therapeutic Class
- Centrally acting Skeletal Muscle Relaxants
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children