Tazocin (4 gm+0.5 gm)/vial (IV Infusion)
4.5 gm vial: ৳ 1,800.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Piperacillin tazobactam |
| Company | Pfizer |
Indications
- Intra-abdominal Infections
- Skin and Skin Structure Infections
- Female Pelvic Infections
- Community-acquired pneumonia
- Nosocomial pneumonia
Pharmacology
- Bactericidal activity against gram-positive and gram-negative bacteria
- Inhibition of septum and cell wall synthesis
- Enhancement and extension of antibiotic spectrum
Dosage & Administration
- Administered by intravenous infusion
- Usual total daily dose for adults
- Recommended duration of treatment for nosocomial pneumonia
- Dosage for pediatric patients
Interaction
- Inactivation of aminoglycosides
- Sequential administration with tobramycin
- Effect on probenecid, anticoagulants, vecuronium, and methotrexate
Contraindications
- History of allergic reactions to penicillins, cephalosporins, or beta-lactamase inhibitors
Side Effects
- Adverse events primarily involving the skin, gastrointestinal system, general disorders, immune hypersensitivity reactions, infections, metabolism, musculoskeletal and connective tissue, psychiatric disorders, vascular disorders, hypotension, and respiratory disorders
Pregnancy & Lactation
- Crosses the placenta
- Insufficient data on drug-associated risk for major birth defects and miscarriage
- Excreted in human milk
Precautions & Warnings
- Serious hypersensitivity reactions
- Severe cutaneous adverse reactions
- Hematological effects
- Nephrotoxicity in critically ill patients
- Clostridium difficile associated diarrhea
Use in Special Populations
- Pediatric use
- Geriatric use
- Renal impairment
- Hepatic impairment
- Patients with cystic fibrosis
Overdose Effects
- Nausea, vomiting, and diarrhea
- Neuromuscular excitability or convulsions
- Supportive and symptomatic treatment
Therapeutic Class
- Broad spectrum penicillins
- Other beta-lactam Antibiotics
Reconstitution
- Administration by intravenous infusion over 30 minutes
- Withdrawal and mixing of diluent
- Immediate usage after reconstitution
- Storage conditions for reconstituted vials
Storage Conditions
- Keep below 30°C temperature
- Away from light and moisture