Elazol 200 mg (Tablet)
Unit Price: ৳ 128.00 (2 x 4: ৳ 1,024.00)
Strip Price: ৳ 512.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of invasive aspergillosis
- Treatment of candidemia and disseminated candidiasis
- Treatment of esophageal candidiasis
- Treatment of serious infections caused by Scedosporium apiospermum and Fusarium Species
- Use in patients intolerant of, or refractory to other therapy
Pharmacology
- Voriconazole binds and inhibits ergosterol synthesis
- Inhibition of CYP450-dependent 14-alpha sterol demethylase
- Depletion of ergosterol in fungal cell membrane
Dosage & Administration
- Oral administration
- Instructions for taking the tablet and powder for suspension
- Different dosage regimens for patients above and below 40 kg body weight
- Injection dosage for various infections
Interaction
- Effect of CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers on Elazol dosage
- Potential increase in concentrations and activity of drugs that are CYP3A4, CYP2C9, and CYP2C19 substrates
- Dosage adjustment with co-administration of certain drugs
Contraindications
- Known hypersensitivity to Voriconazole
- Co-administration with specific drugs
- Risk of serious adverse reactions and loss of efficacy with certain drug combinations
Side Effects
- Common side effects such as abdominal pain, anemia, blurred vision, headache, chest pain, nausea, and diarrhea
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Careful assessment of benefit-risk balance for long-term exposure
- Reported cases of squamous cell carcinoma of the skin with long-term Elazol treatment
Use in Special Populations
- Efficacy not established for children under 12 years of age
Overdose Effects
- No data available on Elazol overdose effects
Therapeutic Class
- Belongs to the therapeutic class of Other Antifungal preparations
Reconstitution
- Instructions for reconstituting the suspension
- Shaking the bottle well before adding water
- Specified amount of water to be added
- Storage instructions for the reconstituted suspension
Storage Conditions
- Storage instructions to keep out of reach of children
- Specified storage temperature and protection from light