Sinlair 10 mg (Tablet)

Unit Price: ৳ 18.00 (2 x 10: ৳ 360.00)
Strip Price: ৳ 180.00

Medicine Details

Category Details
Generic Montelukast sodium
Company Everest pharmaceuticals ltd

Title

  • Sinlair 10 mg Tablet

Categories

  • Medicine
  • Health
  • Pharmaceuticals

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor (CysLT1)

Dosage & Administration

  • Adult dosage: Montelukast 10 mg tablet once daily
  • Pediatric dosage for 6-14 years: Montelukast 5 mg tablet once daily
  • Pediatric dosage for 2-5 years: Montelukast 4 mg tablet once daily
  • Pediatric dosage for 6 months-5 years: Montelukast 4 mg oral granules once daily
  • Hepatic Insufficiency: No dosage adjustment required
  • Renal Insufficiency: No dosage adjustment recommended
  • Elderly use: Similar pharmacokinetic profile and oral bioavailability to younger adults

Interaction

  • No clinically important effects on the pharmacokinetics of several drugs
  • Used concomitantly with a wide range of commonly prescribed drugs without evidence of clinical adverse interactions
  • Phenobarbital decreased the AUC by approximately 40%

Contraindications

  • Hypersensitivity to any component of this product

Side Effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
  • Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor

Pregnancy & Lactation

  • Crosses the placenta in rats and rabbits
  • Use during pregnancy only if clearly needed
  • Caution in nursing mothers

Precautions & Warnings

  • Not indicated for use in the reversal of bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Not to be abruptly substituted for inhaled or oral corticosteroids
  • Not to be used as monotherapy for the treatment of exercise-induced bronchospasm
  • Avoidance in patients with known aspirin sensitivity

Overdose Effects

  • Adverse experiences consistent with the safety profile of the product
  • Supportive measures to be employed in case of overdose

Therapeutic Class

  • Leukotriene receptor antagonists

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S
  • Chemical Structure available

Common Questions

  • What is Sinlair 10 mg Tablet?
  • What is Sinlair 10 mg Tablet used for?
  • How soon can the effect be observed?
  • How long does the effect last?
  • Should it be taken empty stomach?
  • What if a dose is missed?
  • Are there any pregnancy warnings?
  • General Instructions

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