Claxo 4000 Anti-Xa IU/0.4 ml (SC Injection)

0.4 ml pre-filled syringe: ৳ 450.00

Medicine Details

Category Details
Generic Enoxaparin sodium
Company General pharmaceuticals ltd
Also available as
Claxo 6000 anti xa injection

Indications

  • Treatment of deep vein thrombosis
  • Treatment of unstable angina and non-Q-wave myocardial infarction
  • Prevention of thrombus formation in extra-corporeal circulation
  • Prophylaxis of venous thromboembolic disease in surgical patients
  • Prophylaxis of venous thromboembolic disease in medical patients

Composition

  • Each 0.2 ml pre-filled syringe contains Enoxaparin Sodium BP 20 mg
  • Each 0.4 ml pre-filled syringe contains Enoxaparin Sodium BP 40 mg
  • Each 0.6 ml pre-filled syringe contains Enoxaparin Sodium BP 60 mg
  • Each 0.8 ml pre-filled syringe contains Enoxaparin Sodium BP 80 mg

Pharmacology

  • Low molecular weight heparin
  • High anti-Xa activity
  • Low anti-IIa activity
  • Metabolized in the liver

Dosage

  • Subcutaneous administration
  • Oral anticoagulant therapy initiation
  • Dosage based on specific indications

Administration

  • Instructions for self-injection
  • Preparing the injection site
  • Selecting the correct dose
  • Proper injecting technique
  • Post-injection care

Interaction

  • Recommendation to discontinue agents affecting hemostasis before therapy
  • List of medications to avoid or use with caution
  • Need for clinical and laboratory monitoring

Contraindications

  • Hypersensitivity to Enoxaparin Sodium
  • Active major bleeding
  • High risk of uncontrolled hemorrhage

Side Effects

  • Haemorrhage
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Skin reactions at injection sites
  • Neuraxial hematomas risk

Pregnancy & Lactation

  • Pregnancy category B
  • Limited evidence of placental crossing
  • Caution in breastfeeding mothers

Precautions & Warnings

  • Subcutaneous and intravascular administration
  • Avoid intramuscular route
  • Use with caution in conditions with bleeding risk
  • Platelet count monitoring recommendation

Use in Special Populations

  • Dosing in elderly patients
  • Dosing in renal impairment
  • Dosing in hepatic impairment

Overdose Effects

  • Hemorrhagic complications
  • Use of protamine sulfate for neutralization

Therapeutic Class

  • Parenteral anticoagulants

Storage Conditions

  • Cool and dry storage
  • Protection from light and moisture
  • Storage temperature limit at 25°C
  • Keep out of reach of children

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