Tarvanib 100 mg (Tablet)
Unit Price: ৳ 550.00 (1 x 14: ৳ 7,700.00)
Strip Price: ৳ 7,700.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erlotinib |
| Company | Jenphar bangladesh ltd |
| Also available as |
Indications and Usage
- Treatment of metastatic Non-Small Cell Lung cancer with EGFR mutations
- Maintenance treatment for locally advanced or metastatic NSCLC
- Treatment of locally advanced or metastatic NSCLC after chemotherapy failure
- First-line treatment of locally advanced or metastatic pancreatic cancer in combination with gemcitabine
Chemical Name
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)4-quinazolinamine
Kinase Inhibitor
Yes
Kinase Activity Inhibition
Reversible
Targeted Receptors
- EGFR exon 19 deletion
- EGFR exon 21 (L858R)
Drug Form
Quinazolinamine
Dosage Form
Tablet
Recommended Daily Dose for NSCLC
150 mg on an empty stomach
Recommended Daily Dose for Pancreatic Cancer
100 mg once daily in combination with gemcitabine
Dose Adjustment Conditions
- Severe reactions with strong CYP3A4 inhibitors
- Concomitant use with CYP3A4 inducers
- Concurrent cigarette smoking
Interactions with Other Medications
- Anticoagulants
- CYP3A4 inhibitors
- CYP3A4 inducers
- Drugs affecting gastric pH
Common Adverse Reactions
- Rash
- Diarrhea
- Anorexia
- Fatigue
- Dyspnea
- Cough
- Nausea
- Vomiting
Serious Adverse Reactions
- Interstitial Lung Disease
- Renal Failure
- Hepatotoxicity
- Gastrointestinal Perforation
- Bullous and Exfoliative Skin Disorders
- Myocardial Infarction/Ischemia
- Cerebrovascular Accident
- Hemorrhage in Patients Taking Warfarin
Pregnancy Category
D
Special Population Use
- No established pediatric use
- No overall differences in safety or efficacy observed in subjects 65 years and older
Overdose Tolerance
Up to 1000 mg as single oral doses in healthy subjects
Therapeutic Class
Targeted Cancer Therapy
Storage Conditions
Temperature not exceeding 30°C, dry place, protect from light and moisture