Esobest 40 mg/vial (IV Injection)

40 mg vial: ৳ 100.00

Medicine Details

Category Details
Generic Esomeprazole
Company Sharif pharmaceuticals ltd
Also available as
Esobest 20 mg tablet Esobest 20 mg capsule Esobest 40 mg capsule Esobest 40 mg tablet

Title

Esobest 40 mg/vial Injection

Categories

  • Medicine
  • Health
  • Pharmaceutical

Description

Esobest 40 mg/vial Injection is a proton pump inhibitor (PPI) used to relieve chronic heartburn, heal erosive esophagitis, eradicate Helicobacter pylori infection, treat Zollinger-Ellison Syndrome, and manage acid-related dyspepsia, duodenal & gastric ulcers.

Attributes

  • Indications:
    • Relief from chronic heartburn symptoms
    • Healing of erosive esophagitis
    • Maintenance of healing of erosive esophagitis
    • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
    • Zollinger-Ellison Syndrome
    • Acid-related Dyspepsia
    • Treatment of duodenal & gastric ulcers
  • Pharmacology:
    • Proton pump inhibitor
    • Suppresses gastric acid secretion
    • Enteric-coated pellet formulation
    • Metabolized in the liver
    • Excretion in urine and faeces
  • Dosage:
    • Oral dosage form
    • 20 mg or 40 mg once daily for healing of erosive esophagitis
    • 20 mg once daily for maintenance of healing of erosive esophagitis
    • 20 mg once daily for symptomatic GERD
    • Triple Therapy for Helicobacter pylori eradication
    • 20-80 mg once daily for Zollinger-Ellison Syndrome
    • 20-40 mg once daily for acid-related dyspepsia
    • 20 mg once daily for 2-4 weeks for duodenal ulcer
    • 20-40 mg once daily for 4-8 weeks for gastric ulcer
    • IV injection or infusion for specific conditions and age groups
    • Special dosing for risk reduction of rebleeding of gastric or duodenal ulcers following therapeutic endoscopy in adults
  • Administration:
    • Tablet or capsule should be swallowed whole
    • Oral suspension administration instructions
    • IV injection preparation and administration
  • Interaction:
    • Metabolized by CYP2C19 and CYP3A4
    • Inhibition of CYP2C19 by esomeprazole
    • Possible interference with absorption of certain drugs
  • Contraindications:
    • Known hypersensitivity to any of the formulation
  • Side Effects:
    • Headache
    • Diarrhoea
    • Nausea
    • Flatulence
    • Abdominal pain
    • Constipation
    • Dry mouth
  • Pregnancy & Lactation:
    • No adequate and well-controlled studies in pregnant women
    • No teratogenic effects in animal studies
    • Lack of data on excretion in milk
    • Breast-feeding discontinuation recommendation
  • Precautions & Warnings:
    • Symptomatic response does not preclude the presence of gastric malignancy
    • Specific instructions for patients who have difficulty swallowing capsules
    • Antacids usage
  • Use in Special Populations:
    • Safety and effectiveness in paediatric patients not established
    • Comparable safety and efficacy in the elderly
    • Dosage adjustment for severe hepatic insufficiency
    • No altered pharmacokinetics in renal impairment
  • Overdose Effects:
    • Lethal dose in animal studies
    • Symptomatic and supportive treatment recommended
    • No specific antidote known
    • Expected lack of removal by dialysis
  • Storage Conditions:
    • Temperature and environmental storage requirements
    • Protection from light and moisture
    • Keep out of reach of children
  • Chemical Structure:
    • Molecular formula: C17H19N3O3S
    • Chemical structure image
  • Commonly Asked Questions:
    • Uses of Esobest 40 mg/vial Injection
    • Side effects
    • Pregnancy and breastfeeding concerns
    • Time to onset of action
    • Quick tips for usage and precautions

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