Ferox 500 mg/10 ml (IV Injection or Infusion)

10 ml vial: ৳ 700.00

Medicine Details

Category	Details
Generic	Ferric carboxymaltose
Company	Aci limited
Also available as	Ferox 100 mg injection Ferox 750 mg injection Ferox 1 gm injection

Indications

Treatment of iron deficiency anaemia in adult patients with intolerance to oral iron
Treatment of iron deficiency anaemia in adult patients with non-dialysis dependent chronic kidney disease

Description

Colloidal iron (III) hydroxide in complex with Carboxymaltose, a Carbohydrate polymer that releases iron

Dosage & Administration

Stepwise approach to determining individual iron need
Calculation and administration of the iron dose(s)
Post-iron repletion assessments

Interaction

Formal drug interaction studies not performed

Contraindications

Hypersensitivity to the active substance or any of its excipients
Known serious hypersensitivity to other parenteral iron products
Anaemia not attributed to iron deficiency or evidence of iron overload or disturbances in the utilisation of iron

Side Effects

Most common: nausea, headache, dizziness, hypertension, injection site reactions
Uncommon: hypersensitivit, dysgeusia, tachycardia, hypotension, flushing, dyspnoea, abdominal pain, constipation, diarrhea, Pruritus, urticaria, etc.
Rare: anaphylactoid reactions, loss of consciousness, anxiety, phlebitis, syncope, etc.

Pregnancy & Lactation

Benefit/risk evaluation required before use during pregnancy, treatment confined to second and third trimester if benefit outweighs potential risk

Precautions & Warnings

Serious hypersensitivity reactions reported, monitor for signs and symptoms of hypersensitivity
Transient elevations in systolic blood pressure, monitor patients for hypertension following each administration
In the 24 hours following administration, laboratory assays may overestimate serum iron and transferrin bound iron

Use in Special Populations

Single maximum daily injection dose of 200 mg iron not to be exceeded in haemodialysis-dependent chronic kidney disease patients
Not recommended in children under 14 years

Overdose Effects

Excessive dosages may lead to accumulation of iron in storage sites potentially leading to hemosiderosis, monitor iron parameters and consider use of an iron chelator

Therapeutic Class

Parenteral Iron Preparations

Storage Conditions

Store below 30°C in a cool, dry place, away from light, and out of reach of children