Ferox 100 mg/2 ml (IV Injection or Infusion)

2 ml vial: ৳ 410.00

Medicine Details

Category Details
Generic Ferric carboxymaltose
Company Aci limited
Also available as
Ferox 500 mg injection Ferox 750 mg injection Ferox 1 gm injection

Indications

  • Treatment of iron deficiency anemia in adult patients
  • Intolerance to oral iron or unsatisfactory response to oral iron
  • Non-dialysis dependent chronic kidney disease

Description

  • Colloidal iron (III) hydroxide in complex with Carboxymaltose
  • Carbohydrate polymer that releases iron

Dosage & Administration

  • Stepwise approach to determination and administration of iron dose
  • Individual iron need determination based on body weight and haemoglobin level
  • Calculation and administration of maximum individual iron dose(s)
  • Post-iron repletion assessments
  • Limitations on maximum recommended cumulative dose per week

Interaction

  • Formal drug interaction studies not performed

Contraindications

  • Hypersensitivity to the active substance or any excipients
  • Serious hypersensitivity to other parenteral iron products
  • Anaemia not attributed to iron deficiency
  • Evidence of iron overload or disturbances in iron utilization

Side Effects

  • Mild and infrequent side effects
  • Common side effects: nausea, headache, dizziness, hypertension, injection site reactions
  • Uncommon side effects: hypersensitivity, tachycardia, hypotension, dyspepsia, diarrhea
  • Rare side effects: anaphylactoid reactions, loss of consciousness, anxiety, phlebitis

Pregnancy & Lactation

  • No adequate and well-controlled trials in pregnant women
  • Careful benefit/risk evaluation required before use during pregnancy
  • Unlikely risk to the breastfed child based on limited data

Precautions & Warnings

  • Serious hypersensitivity reactions reported
  • Monitoring for signs and symptoms of hypersensitivity and hypertension
  • Potential overestimation of serum iron and transferrin bound iron in laboratory assays

Use in Special Populations

  • Limitation on maximum daily injection dose in haemodialysis-dependent chronic kidney disease patients
  • Not recommended in children under 14 years

Overdose Effects

  • Excessive dosages may lead to accumulation of iron in storage sites
  • Monitoring of iron parameters for recognition of iron accumulation
  • Consideration of use of an iron chelator if iron accumulation has occurred

Therapeutic Class

  • Parenteral Iron Preparations

Storage Conditions

  • Store in a cool and dry place, away from light
  • Do not freeze
  • Keep out of the reach of children

Related Brands