F-Son 27.5 mcg/spray (Nasal Spray)
120 metered sprays: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluticasone furoate |
| Company | Drug international ltd |
Indications
- Treatment of seasonal allergic rhinitis
- Treatment of perennial allergic rhinitis
- Prophylactic therapy for asthma in patients aged 5 years and older
Description
- Synthetic fluorinated corticosteroid
- Aqueous suspension of microfine F-Son
- Topical administration to the nasal mucosa
- Metering and atomizing spray pump
- Need for priming the pump before first use or after non-use period
- 120 metered sprays per bottle
Pharmacology
- Potent anti-inflammatory activity
- Wide range of actions on multiple cell types
- Actions on mast cells, eosinophils, neutrophils, macrophages, lymphocytes, and mediators involved in inflammation
Dosage
- Different dosages for adults and children
- Daily maintenance treatment for asthma
- Prophylactic therapy for asthma in patients aged 5 years and older
- Dosage based on asthma severity
- Recommended starting dose based on previous asthma drug therapy and disease severity
- Maximum daily dosage
- Dosage adjustment for pediatric patients
- Orally inhaled route of administration
Administration
- Instructions for using the nasal spray
- Cleaning instructions for the nasal spray
- Regular intervals of use for effectiveness
Interaction
- Potent inhibitors of cytochrome P450 3A4 (CYP3A4)
- Coadministration of ritonavir
- Cautions for coadministration of other potent CYP3A4 inhibitors
- Device priming instructions
Contraindications
- Hypersensitivity to any of its ingredients
Side Effects
- Limited absorption into the body
- Increased incidence of nosebleeds
- Adverse reactions in adult, adolescent, and pediatric subjects
- Common adverse reactions
Pregnancy & Lactation
- Category C pregnancy classification
- Lack of adequate and well-controlled studies in pregnant women
- Potential benefit justifying potential risk
- Unknown excretion of Fluticasone Furoate in human breast milk
- Cautions for nursing women
Precautions & Warnings
- Rare hypersensitivity and contact dermatitis
- Reported instances of wheezing, nasal septum perforation, cataracts, and glaucoma
- Minimal systemic effects with recommended doses
- Avoidance of larger than recommended doses
Use in Special Populations
- Caution in dose selection for the elderly
- Consideration for decreased hepatic, renal, or cardiac function
- Consideration for concomitant disease or other drug therapy
- Caution in severe hepatic impairment
- No dosage adjustment required in renal impairment
Therapeutic Class
- Nasal Steroid Preparations
Storage Conditions
- Temperature not exceeding 30°C
- Protection from light and moisture
- Keep out of the reach of children