Olmefast H 20 mg+12.5 mg (Tablet)
Unit Price: ৳ 8.50 (3 x 10: ৳ 255.00)
Strip Price: ৳ 85.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Olmesartan medoxomil hydrochlorothiazide |
| Company | Goodman pharmaceuticals ltd |
Indications
- Treatment of hypertension
Pharmacology
- Block vasoconstrictor and aldosterone-secreting effects of angiotensin-II
- Thiazide diuretic affecting renal tubular mechanisms
- Reduction of plasma volume and increase in renin activity
- Angiotensin-II receptor antagonist linked to potassium loss reduction
Dosage & Administration
- Usual starting dose 20/12.5 mg once daily
- Individualized dosing
- Titration based on blood pressure response
Interaction
- Olmesartan has no significant drug interactions reported
- Hydrochlorothiazide may interact with alcohol, barbiturates, narcotics, antidiabetic drugs, other antihypertensive drugs, corticosteroids, ACTH, and lithium
Contraindications
- Hypersensitivity to any component of the product
- Anuria or hypersensitivity to sulfonamide-derived drugs
Side Effects
- Nausea
- Headache
- Dizziness
- Hyperuricemia
- Upper respiratory tract infection
- Urinary tract infection
- Chest pain
- Back pain
- Peripheral edema
- Abdominal pain
- Dyspepsia
- Gastroenteritis
- Diarrhea
Pregnancy & Lactation
- Safety and effectiveness not established
- Discontinuation during pregnancy and lactation
Precautions & Warnings
- Periodic determination of serum electrolytes
- Risk of hypokalemia, hyponatremia, and hypochloremic alkalosis
- Potential hyperuricemia in certain patients
- Impaired renal function
Use in Special Populations
- Usual regimens may be followed for renal impairment patients with creatinine clearance >30 ml/min
- Loop diuretics preferred to thiazides in severe renal impairment
- No dosage adjustment necessary with hepatic impairment
- Safety and effectiveness not established in pediatric patients
- Caution in dose selection for elderly patients
Overdose Effects
- Manifestation of hypotension and tachycardia in Olmesartan overdose
- Signs and symptoms caused by electrolyte depletion in Hydrochlorothiazide overdose
- Risk of accentuated cardiac arrhythmias if digitalis also administered
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Store in a cool and dry place
- Protect from light and moisture
- Keep out of the reach of children