Iroject 500 mg/10 ml (IV Injection or Infusion)

10 ml vial: ৳ 700.00

Medicine Details

Category Details
Generic Ferric carboxymaltose
Company Popular pharmaceuticals ltd
Also available as
Iroject 1 gm injection

Indications

  • Treatment of iron deficiency anaemia in adult patients
  • Intolerance to oral iron or unsatisfactory response to oral iron
  • Non-dialysis dependent chronic kidney disease

Description

  • Colloidal iron (III) hydroxide in complex with Carboxymaltose
  • Carbohydrate polymer that releases iron

Dosage & Administration

  • Stepwise approach for posology
  • Determination of individual iron need based on body weight and haemoglobin level
  • Calculation and administration of iron dose(s)
  • Maximum recommended cumulative dose per week
  • Post-iron repletion assessments

Interaction

  • Formal drug interaction studies not performed

Contraindications

  • Hypersensitivity to the active substance or any of its excipients
  • Serious hypersensitivity to other parenteral iron products
  • Anaemia not attributed to iron deficiency
  • Evidence of iron overload or disturbances in iron utilisation

Side Effects

  • Infrequent, usually mild and generally do not cause patients to stop treatment
  • Common side effects: nausea, headache, dizziness, hypertension
  • Uncommon side effects: hypersensitivity, dysgeusia, tachycardia, hypotension
  • Rare side effects: anaphylactoid reactions, loss of consciousness, anxiety

Pregnancy & Lactation

  • No adequate and well-controlled trials in pregnant women
  • Benefit/risk evaluation required before use during pregnancy
  • Unlikely risk to the breast-fed child based on limited data

Precautions & Warnings

  • Serious hypersensitivity reactions reported
  • Monitor patients for signs and symptoms of hypersensitivity
  • Transient elevations in systolic blood pressure
  • Laboratory test alterations following administration of Iroject

Use in Special Populations

  • Maximum daily injection dose for haemodialysis-dependent chronic kidney disease patients
  • Not recommended in children under 14 years

Overdose Effects

  • Accumulation of iron in storage sites potentially leading to hemosiderosis
  • Monitoring of iron parameters such as serum ferritin and transferrin saturation may assist in recognising iron accumulation

Therapeutic Class

  • Parenteral Iron Preparations

Storage Conditions

  • Store in a cool (below 30°C) and dry place
  • Away from light
  • Do not freeze
  • Keep out of the reach of children

Related Brands