Topimax 25 mg (Tablet)
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Topiramate |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of epilepsy in adults and children
- Prophylaxis of migraine headaches
Pharmacology
- Blocks neuronal excitability to prevent seizures and migraines
- Stimulates GABA-A receptor activity
- Reduces glutamate activity at AMPA and kainate receptors
- Inhibition of voltage-dependent sodium channels
Dosage & Administration
- Initial target dose for topiramate monotherapy in adults
- Recommended initial target dose range for topiramate monotherapy in children
- Usual total daily dose for adjunctive therapy in adults and children
- Dosage titration for optimal clinical response
Interaction
- Effect on steady-state plasma concentrations of other antiepileptic drugs
- Caution when used with CNS depressants, oral contraceptives, lithium, hydrochlorothiazide, metformin, pioglitazone, glibenclamide
- Potential increased risk of nephrolithiasis
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Nausea, abdominal pain, dyspepsia, diarrhea
- Dry mouth, taste disturbance, weight loss, anorexia
- Headache, fatigue, dizziness, speech disorder
- Visual disturbance, drowsiness, insomnia, anxiety, depression
- Impaired memory & concentration, suicidal ideation
- Metabolic acidosis, alopecia, leucopenia, thrombocytopenia, serious skin reactions
Pregnancy & Lactation
- Not recommended for use during pregnancy and breastfeeding
Precautions & Warnings
- Gradual withdrawal to minimize potential for increased seizure frequency
- Potential for sedative effects and visual disturbances
- Advice against driving, operating machinery, or high-risk activities
Overdose Effects
- Severe metabolic acidosis
- Immediate stomach emptying in case of recent ingestion
- Activated charcoal for adsorption
- Supportive treatment and haemodialysis
Therapeutic Class
- Adjunct anti-epileptic drugs
Storage Conditions
- Storage temperature below 30°C
- Protection from light and moisture
- Keep out of the reach of children