Xarelta 2.5 mg (Tablet)

Unit Price: ৳ 8.00 (2 x 14: ৳ 224.00)
Strip Price: ৳ 112.00

Medicine Details

Indications

  • Prevention of atherothrombotic events after an Acute Coronary Syndrome
  • Stroke and systemic embolism risk reduction in nonvalvular atrial fibrillation
  • Deep vein thrombosis (DVT) and pulmonary embolism (PE) treatment
  • Prophylaxis of DVT in patients undergoing knee or hip replacement surgery

Pharmacology

  • Highly selective direct factor Xa inhibitor
  • Interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade

Dosage & Administration

  • Rivaroxaban 2.5 mg recommended dose
  • Rivaroxaban 10-20 mg dosage for nonvalvular atrial fibrillation
  • Rivaroxaban 10-20 mg treatment dosage for DVT & PE
  • Prophylaxis dosage of DVT following hip or knee replacement surgery

Interaction

  • Concomitant use with P-gp and CYP3A4 inhibitors
  • Concomitant use with P-gp and strong CYP3A4 inducers
  • Concomitant use with anti-platelet agents, heparin, and fibrinolytic therapy

Contraindications

  • Known hypersensitivity to Rivaroxaban or any excipients
  • Active pathological bleeding

Side Effects

  • Increased chance of bleeding
  • Spinal or epidural hematoma risk
  • Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation

Pregnancy & Lactation

  • Category C drug
  • Unknown excretion in human milk

Precautions & Warnings

  • Increased risk of fatal bleeding
  • Monitoring for signs or symptoms of neurological impairment
  • Not recommended in patients with pulmonary embolism who present with hemodynamic instability

Overdose Effects

  • Hemorrhage risk
  • No specific antidote available

Therapeutic Class

  • Oral Anticoagulants

Storage Conditions

  • Store in a cool and dry place below 30°C
  • Protected from light
  • Keep away from the reach of children

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