Xarelta 15 mg (Tablet)
Unit Price: ৳ 35.00 (1 x 14: ৳ 490.00)
Strip Price: ৳ 490.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rivaroxaban |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Prevention of atherothrombotic events after Acute Coronary Syndrome (ACS)
- Reduction of risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
- Treatment and prevention of deep vein thrombosis (DVT) & pulmonary embolism (PE)
- Prophylaxis of DVT after knee or hip replacement surgery
Pharmacology
- Highly selective direct factor Xa inhibitor
- Interrupts intrinsic and extrinsic pathway of blood coagulation cascade
- Does not inhibit thrombin or platelets
Dosage & Administration
- Recommended doses for different conditions and patient profiles
- May be taken with or without food
Interaction
- Concomitant use with specific drugs increases exposure and pharmacodynamic effects
- Co-administration with certain drugs decreases efficacy
- Increased risk of bleeding with other specific drug classes
Contraindications
- Known hypersensitivity to Rivaroxaban or excipients
- Active pathological bleeding
Side Effects
- Increased chance of bleeding
- Spinal or epidural hematoma
- Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation
Pregnancy & Lactation
- Pregnancy category C drug
- No established dosing for pregnant women
- Unknown excretion in human milk
- Safety and efficacy not established in breastfeeding women
Precautions & Warnings
- Risk of thrombotic events with early discontinuation
- Increased risk of fatal bleeding in the presence of specific risk factors
- Monitoring of neurological impairment in neuraxial anesthesia
- Not recommended in specific patient profiles
Overdose Effects
- May lead to hemorrhage
- Systemic exposure not further increased at single doses >50 mg
- No specific antidote available
- Consideration of activated charcoal for reducing absorption
Therapeutic Class
- Oral Anticoagulants
Storage Conditions
Cool and dry place below 30°C, protected from light, keep away from children