Xarelta 20 mg (Tablet)

Unit Price: ৳ 45.00 (1 x 14: ৳ 630.00)
Strip Price: ৳ 630.00

Medicine Details

Title

  • Xarelta 2.5 mg
  • Xarelta 10-20 mg

Categories

  • Medicine
  • Anticoagulant
  • Cardiovascular medication

Dimensions

  • N/A

Color Options

  • N/A

Functions

  • Prevention of atherothrombotic events after Acute Coronary Syndrome with elevated cardiac biomarkers
  • Risk reduction of stroke and systemic embolism in nonvalvular atrial fibrillation
  • Treatment and prophylaxis of Deep Vein Thrombosis and Pulmonary Embolism
  • Prophylaxis of DVT after knee or hip replacement surgery

Materials

  • Rivaroxaban

Technical Specifications

  • Highly selective direct factor Xa inhibitor
  • Interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade
  • Does not inhibit thrombin or platelets

Design Elements

  • N/A

Usability Features

  • Oral administration
  • May be taken with or without food

Dosage

  • Rivaroxaban 2.5 mg: 2.5 mg twice daily co-administered with Aspirin alone or with Aspirin plus Clopidogrel or Ticlopidine
  • Rivaroxaban 10-20 mg: varies based on indication and patient renal function

Interaction

  • Contraindicated with combined P-gp and CYP3A4 inhibitors
  • Avoid co-administration with combined P-gp and strong CYP3A4 inducers
  • Increased risk of bleeding with concomitant use of certain drugs

Contraindications

  • Known hypersensitivity to Rivaroxaban or any excipients
  • Active pathological bleeding

Side Effects

  • Increased chance of bleeding
  • Spinal or epidural hematoma
  • Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation

Pregnancy & Lactation

  • Pregnancy category C drug
  • No established dosing for pregnant or breastfeeding women

Precautions & Warnings

  • Increased risk of thrombotic events with early discontinuation
  • Increased risk of fatal bleeding with certain risk factors

Overdose Effects

  • May lead to hemorrhage
  • Limited systemic exposure at single doses >50 mg
  • No specific antidote available

Therapeutic Class

  • Oral Anticoagulants

Storage Conditions

  • Cool and dry place below 30°C, protected from light

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