Exforge 5 mg+160 mg (Tablet)
Unit Price: ৳ 70.75 (2 x 14: ৳ 1,981.00)
Strip Price: ৳ 990.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate valsartan |
| Company | Novartis bangladesh ltd |
| Also available as |
Indications
- Treatment of hypertension
Pharmacology
- Amlodipine is a dihydropyridine calcium channel blocker
- Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of Angiotensin II
Dosage & Administration
- Once daily doses of 2.5 mg - 10 mg for Amlodipine
- Doses of 80 mg-320 mg for Valsartan
- Maximum dosage of 10/320 mg once daily
- Can be administered with or without food
- May be administered with other antihypertensive agents
Elderly patients
- Initiate therapy at 2.5 mg of Amlodipine
Renal Impairment
- No initial dosage adjustment for mild or moderate impairment
- Titrate slowly in severe impairment
Hepatic Impairment
- No initial dosage adjustment for mild or moderate insufficiency
- Titrate slowly in hepatic impairment
Interaction
- No drug interaction studies conducted with combination
Contraindications
- Hypersensitivity to any components of the product
Side Effects
- Mild and transient side effects
- Common side effects include peripheral edema, nasal congestion, sore throat, dizziness
Pregnancy & Lactation
- Pregnancy Category D
- Potential adverse effects on nursing infant
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Assess for hypotension
- Warn patients with severe obstructive coronary artery disease about risk of myocardial infarction
- Titrate slowly in patients with impaired hepatic or severely impaired renal function
Use in Special Populations
- Safety and effectiveness in paediatric patients not established
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children