Exforge 10 mg+160 mg (Tablet)
Unit Price: ৳ 79.09 (2 x 14: ৳ 2,214.52)
Strip Price: ৳ 1,107.26
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate valsartan |
| Company | Novartis bangladesh ltd |
| Also available as |
Indications
- Treatment of hypertension
- Not indicated for initial therapy of hypertension
Pharmacology
- Amlodipine is a calcium channel blocker
- Valsartan blocks vasoconstrictor and aldosterone-secreting effects
- Both have been shown to lower blood pressure
Dosage & Administration
- Effective doses for Amlodipine: 2.5 mg - 10 mg
- Effective doses for Valsartan: 80 mg - 320 mg
- Antihypertensive effects increase with increasing doses
- Dosage can be increased after 1 to 2 weeks of therapy
- May be administered with or without food
- May be administered with other antihypertensive agents
- Initiate Amlodipine therapy at 2.5 mg for elderly patients
- No initial dosage adjustment for mild or moderate renal impairment
- Titrate slowly in patients with severe renal impairment or hepatic impairment
Interaction
- No drug interaction studies conducted with Amlodipine and Valsartan combination
Contraindications
- Contraindicated in patients who are hypersensitive to any components
Side Effects
- Common side effects include: peripheral edema, nasal congestion, sore throat, discomfort when swallowing, dizziness
Pregnancy & Lactation
- Pregnancy Category D
- It is not known whether Amlodipine or Valsartan is excreted in human milk
- Considerations for discontinuing nursing or the drug
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Assess for hypotension
- Warn patients with severe obstructive coronary artery disease about the risk of myocardial infarction or increased angina
- Titrate slowly in patients with impaired hepatic or severely impaired renal function
Use in Special Populations
- Safety and effectiveness in paediatric patients not established
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children